Evidence map›Paper›PMID 35737165›Full record

ArticleBulletin of experimental biology and medicine2022

Indicators of Immune and Neurohumoral Profile in Women of Fertile Age with Functional Disorders of the Autonomic Nervous System Associated with Polymorphic Variants of the HTR2A (rs7997012) and TP53 (rs1042522) Genes.

O V Dolgikh, N V Zaitseva, N A Nikonoshina, V B Alekseev

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

O V DolgikhState Scientific Center of Medical and Preventive Health Risk Management Technologies, Perm, Russia.
N V ZaitsevaState Scientific Center of Medical and Preventive Health Risk Management Technologies, Perm, Russia.
N A NikonoshinaState Scientific Center of Medical and Preventive Health Risk Management Technologies, Perm, Russia. nat08.11@yandex.ru.
V B AlekseevState Scientific Center of Medical and Preventive Health Risk Management Technologies, Perm, Russia.
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In women of fertile age with functional disorders of the autonomic nervous system (ANS), a complex of indicators of the immune and neurohumoral profile associated with polymorphic variants of the HTR2A (rs7997012) and TP53 (rs1042522) genes was revealed. In patients with the diagnosis "G90.8. Other disorders of the autonomic nervous system", the neurohumoral profile is characterized by excessive content of cortisol and serotonin (p<0.05), which indicates the development of the hypersympathicotonic variant of autonomic regulation disorders. The cellular immune profile in the examined individuals was characterized by a significant decrease in the content of CD3

Indexed as

Autonomic Nervous System DiseasesPolymorphism, Single NucleotideReceptor, Serotonin, 5-HT2ATumor Suppressor Protein p53FemaleGenotypeHumansHydrocortisoneImmunoglobulin GImmunoglobulin MSerotoninHTR2A protein, humanHydrocortisoneImmunoglobulin GImmunoglobulin MReceptor, Serotonin, 5-HT2ASerotoninTP53 protein, humanTumor Suppressor Protein p53apoptosisautonomic nervous systemgenetic polymorphismimmune systemserotonin

Identifiers

PMID35737165
OpenAlexW4283324413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.