Evidence map›Paper›PMID 35737132›Full record

ArticleArchives of women's mental health2022

Licit and illicit drug use across trimesters in pregnant women endorsing past-year substance use: Results from National Survey on Drug Use and Health (2009-2019).

MacKenzie R Peltier, Walter Roberts, Terril L Verplaetse, Catherine Burke, Yasmin Zakiniaeiz, Kelly Moore, Sherry A McKee

Open access · greenAbstract read
In one paragraph

Article in Archives of women's mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. Cannabis and Nicotine Substance Use Coercion During the Perinatal Period.Women's health reports (New Rochelle, N.Y.) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

MacKenzie R PeltierDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA. mackenzie.peltier@yale.edu.
Walter RobertsDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Terril L VerplaetseDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Catherine BurkeDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Yasmin ZakiniaeizDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Kelly MooreDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Sherry A McKeeDepartment of Psychiatry, Yale School of Medicine, 2 Church Street South, Suite 201, New Haven, CT, 06519, USA.
Yale University · USEast Tennessee State University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale-SCORE Resource Support CoreU54AA027989 · NIAAA · YALE UNIVERSITY · PI Sherry Ann McKee · 2020 to 2026
$13.0M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Yale SCOR on Gender-Sensitive Treatment for Tobacco DependenceP50DA033945 · NIDA · YALE UNIVERSITY · PI MCKEE, SHERRY ANN · 2012 to 2017
$6.5M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Does Guanfacine, an alpha2 adrenergic agonist, attenuate stress-induced drinking?R01AA022285 · NIAAA · YALE UNIVERSITY · PI MCKEE, SHERRY ANN · 2014 to 2017
$1.5M
Behavioral and Neurochemical Mechanisms Underlying Stress-Precipitated DrinkingK01AA025670 · NIAAA · YALE UNIVERSITY · PI VERPLAETSE, TERRIL L · 2018 to 2023
$882k
Sex Differences in Alcohol Use Disorder Neurodegeneration using Multimodal PET and DTI NeuroimagingK01AA029706 · NIAAA · YALE UNIVERSITY · PI Yasmin Zakiniaeiz · 2022 to 2026
$881k
Developing a mobile alcohol biosensor platform for use in medication testing researchK23AA026890 · NIAAA · YALE UNIVERSITY · PI ROBERTS, WALTER MCRAINEY · 2019 to 2023
$827k
Does endotoxin administration increase alcohol consumption in individuals with AUD?R03AA028361 · NIAAA · YALE UNIVERSITY · PI VERPLAETSE, TERRIL L · 2021 to 2022
$168k
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K01 AA025670NIAAA NIH HHS K01 AA029706NIAAA NIH HHS K23 AA026890NIAAA NIH HHS P01AA02747307NIAAA NIH HHS R01 AA022285NIAAA NIH HHS R03 AA028361NIAAA NIH HHS R03AA028361NIAAA NIH HHS U54 AA027989NIDA NIH HHS P50 DA033945NIDA NIH HHS P50DA033945NIDA NIH HHS T32 DA007238NIDA NIH HHS T32DA007238
6 · The paper itself

Abstract

purposeGiven the health consequences, perinatal substance use is a significant public health concern, especially as substance use rates increase among women; ongoing data regarding the rates of substance use across trimesters of pregnancy is needed.

methodsThe present study utilized cross-sectional population-based data from the National Survey of Drug Use and Health (NSDUH) between 2009 and 2019. We aimed to explore both licit and illicit substance use assessed within each trimester among women endorsing past-year substance use. The NSDUH sample included 8,530 pregnant women.

resultsPerinatal substance use was less prevalent among women in later trimesters; however, past-month substance use was observed for all substances across trimesters. The prevalence of past-month licit substance use among pregnant women ranged from 5.77 to 22.50% and past-month illicit substance use ranged from 4.67 to 14.81%. In the second trimester, lower odds of past-month substance use were observed across tobacco, alcohol, and marijuana (odds ratios [ORs] ranging from 0.29 to 0.47), when compared to the first trimester. A similar lower rate of past-month substance use was observed in the third trimester compared to the first trimester, across tobacco, alcohol, and marijuana use, as well as cocaine, prescription pain medication, and tranquilizer use (ORs ranging from 0.02 to 0.42). The likelihood of polysubstance use was lower among women in the second and third trimesters compared to the first trimester (ORs ranging from 0.09 to 0.46).

conclusionFindings indicate that a minority of women continue to use substances across all trimesters. This is especially true among women using licit substances and marijuana. These results highlight the need for improved interventions and improved access to treatment for these women.

Indexed as

CannabisIllicit DrugsMarijuana SmokingSubstance-Related DisordersCross-Sectional StudiesFemaleHumansPregnancyPregnant PeopleIllicit DrugsIllicit substancesLicit substancesPregnancySubstance useTrimester

Identifiers

PMID35737132
PMCPMC9359119
OpenAlexW4283314080

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.