Evidence map›Paper›PMID 35737066›Full record

ArticleToxins2022

An Interlaboratory Comparison Study of Regulated and Emerging Mycotoxins Using Liquid Chromatography Mass Spectrometry: Challenges and Future Directions of Routine Multi-Mycotoxin Analysis including Emerging Mycotoxins.

David Steiner, Armin Humpel, Eleonore Stamminger, Anna Schoeberl, Gerlinde Pachschwoell, Anita Sloboda, Christy Swoboda, Jolene Rigg, Dawei Zhang, Yahong Wang and 16 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 6 countries.

David SteinerRomer Labs Diagnostic GmbH, Analytical Service Department, Technopark 5, 3430 Tulln, Austria.ORCID 0000-0002-7941-2790
Armin HumpelRomer Labs Diagnostic GmbH, Analytical Service Department, Technopark 5, 3430 Tulln, Austria.
Eleonore StammingerRomer Labs Division Holding GmbH, Marketing Department, Erber Campus 1, 3131 Getzersdorf, Austria.
Anna SchoeberlRomer Labs Division Holding GmbH, Technical Support Department, Technopark 5, 3430 Tulln, Austria.
Gerlinde PachschwoellRomer Labs Diagnostic GmbH, Analytical Service Department, Technopark 5, 3430 Tulln, Austria.
Anita SlobodaRomer Labs Diagnostic GmbH, Analytical Service Department, Technopark 5, 3430 Tulln, Austria.
Christy SwobodaRomer Labs US Inc., Analytical Service Department, 1301 Stylemaster Drive, Union, MO 63084, USA.
Jolene RiggRomer Labs US Inc., Analytical Service Department, 1301 Stylemaster Drive, Union, MO 63084, USA.
Dawei ZhangRomer Labs Analytical Service (Wuxi) Ltd., No. 6-1 Chunyu Road, Wuxi 214000, China.
Yahong WangRomer Labs Analytical Service (Wuxi) Ltd., No. 6-1 Chunyu Road, Wuxi 214000, China.
Joshua DavisRomer Labs Division Holding GmbH, Marketing Department, Erber Campus 1, 3131 Getzersdorf, Austria.
Michael SulyokDepartment of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, 3430 Vienna, Austria.ORCID 0000-0002-3302-0732
Rudolf KrskaDepartment of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, 3430 Vienna, Austria.ORCID 0000-0001-6843-9755
Brian QuinnInstitute for Global Food Security, Queens University Belfast, Belfast BT7 1NN, UK.
Brett GreerInstitute for Global Food Security, Queens University Belfast, Belfast BT7 1NN, UK.
Christopher T ElliottInstitute for Global Food Security, Queens University Belfast, Belfast BT7 1NN, UK.ORCID 0000-0003-0495-2909
Zbynek DzumanDepartment of Food Analysis and Nutrition, University of Chemistry and Technology, Prague, Technicka 3, 16628 Prague 6, Czech Republic.
Jana HajslovaDepartment of Food Analysis and Nutrition, University of Chemistry and Technology, Prague, Technicka 3, 16628 Prague 6, Czech Republic.
Andreas GschaiderLVA GmbH, Department for Residue Analysis, Magdeburggasse 10, 3400 Klosterneuburg, Austria.
Carina FechnerLVA GmbH, Department for Residue Analysis, Magdeburggasse 10, 3400 Klosterneuburg, Austria.
Lisa ForstnerLVA GmbH, Department for Residue Analysis, Magdeburggasse 10, 3400 Klosterneuburg, Austria.
Elisabeth VargaDepartment of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Straße 38-40, 1090 Vienna, Austria.ORCID 0000-0001-6046-3259
Piotr JedziniakDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland.ORCID 0000-0001-5212-2913
Katarzyna PietruszkaDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland.
Adrianna RudawskaDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland.
Alexandra MalachováFFoQSI-Austrian Competence Centre for Feed and Food Quality, Safety & Innovation, FFoQSI GmbH, 3430 Tulln, Austria.
Queen's University Belfast · GBAustrian Competence Centre of Food Safety · ATNational Veterinary Research Institute · PLAnalytical Services · USUniversity of Chemistry and Technology, Prague · CZAgency for Quality Assurance and Accreditation Austria · ATBOKU University · ATJiangnan University · CNUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present interlaboratory comparison study involved nine laboratories located throughout the world that tested for 24 regulated and non-regulated mycotoxins by applying their in-house LC-MS/MS multi-toxin method to 10 individual lots of 4 matrix commodities, including complex chicken and swine feed, soy and corn gluten. In total, more than 6000 data points were collected and analyzed statistically by calculating a consensus value in combination with a target standard deviation following a modified Horwitz equation. The performance of each participant was evaluated by a z-score assessment with a satisfying range of ±2, leading to an overall success rate of 70% for all tested compounds. Equal performance for both regulated and emerging mycotoxins indicates that participating routine laboratories have successfully expanded their analytical portfolio in view of potentially new regulations. In addition, the study design proved to be fit for the purpose of providing future certified reference materials, which surpass current analyte matrix combinations and exceed the typical scope of the regulatory framework.

Indexed as

MycotoxinsAnimalsChromatography, High Pressure LiquidChromatography, LiquidGlutensHumansSwineTandem Mass SpectrometryZea maysGlutensMycotoxinscertified reference materialcomplex feedinternal standardmethod harmonizationz-score

Identifiers

PMID35737066
PMCPMC9229327
OpenAlexW4282825820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.