Evidence map›Paper›PMID 35737045›Full record

ArticleToxins2022

Inhibition of

Susana Lorán, Juan José Carramiñana, Teresa Juan, Agustín Ariño, Marta Herrera

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Climate Change and Aflatoxin BFood science & nutrition · 2026
    Review
  4. Article
  5. Review
  6. Exploring the Characteristics of AtoxigenicJournal of fungi (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Susana LoránInstituto Agroalimentario de Aragón-IA2, Facultad de Veterinaria, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain.ORCID 0000-0002-1961-8551
Juan José CarramiñanaInstituto Agroalimentario de Aragón-IA2, Facultad de Veterinaria, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain.ORCID 0000-0002-3320-9295
Teresa JuanInstituto Agroalimentario de Aragón-IA2, Facultad de Veterinaria, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain.ORCID 0000-0002-4985-298X
Agustín AriñoInstituto Agroalimentario de Aragón-IA2, Facultad de Veterinaria, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain.ORCID 0000-0001-6325-7100
Marta HerreraInstituto Agroalimentario de Aragón-IA2, Facultad de Veterinaria, Universidad de Zaragoza-CITA, 50013 Zaragoza, Spain.ORCID 0000-0002-2469-0363
Universidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aflatoxins represent a significant risk to food safety, and strategies are being implemented to reduce their entry into the food chain. The aim of this study was to evaluate the in vitro effect of four essential oils (EOs) (lavandins Grosso and Abrial, Origanum virens, and Rosmarinus officinalis) and four natural phenolic acids (PAs) (caffeic, chlorogenic, ferulic, and p-coumaric) on the growth and aflatoxins (B1, B2, G1, and G2) production by Aspergillus parasiticus. Minimal inhibitory concentration (MIC) and minimal fungicide concentration (MFC) were determined by the broth macrodilution method. Additionally, the mycelia weight was determined at concentration levels lower than MIC. The antiaflatoxigenic activity was evaluated in the two concentrations of the EOs right before MIC and at concentrations below the MIC value for the PAs. To this end, in-house validated methodology based on high-performance liquid chromatography with post-column photochemical derivatization and fluorescence detection (HPLC-PHRED-FLD) was used. EOs of O. virens and lavandins (Grosso and Abrial) completely inhibited mold growth. In addition, a significant reduction in mycelial mass (p < 0.05) was observed for all EOs and PAs at different concentrations. In all cases except for lavandin Abrial, EO concentrations just before the MIC value strongly reduced (p < 0.05) aflatoxins synthesis. Aflatoxins production was completely inhibited by all PAs at a concentration of 20 mM; although at low concentrations, mycotoxin production was stimulated in some cases. The present study provides a scientific basis for further study of the inhibiting mechanisms.

Indexed as

AflatoxinsOils, VolatileAntifungal AgentsAspergillusAflatoxinsAntifungal AgentsOils, Volatileantiaflatoxigenicantifungalessential oilsphenolic acids

Identifiers

PMID35737045
PMCPMC9227641
OpenAlexW4281624510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.