ArticleToxins2022
Validation of a Culturally Relevant Snakebite Envenomation Clinical Practice Guideline in Brazil.
Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 20 citations in OpenAlex.
- Effectiveness, safety, and implementation outcomes of a decentralization program to deliver antivenoms in the Western Brazilian Amazonia: The SAVING program.PLoS neglected tropical diseases · 2026Article
- Ethical considerations in decentralizing antivenom treatment in indigenous territories of the Brazilian Amazonia.PLoS neglected tropical diseases · 2026Article
- Snakes and snakebites in the munduruku cosmology and medicine, central Brazilian Amazonia.PLoS neglected tropical diseases · 2026Article
- Snakebite Envenomations In The Brazilian Amazon: A Little Less Neglected.Revista da Sociedade Brasileira de Medicina Tropical · 2026Review
- Clinical characteristics and long-term disabilities in children followingThe journal of venomous animals and toxins including tropical diseases · 2026Article
- Therapeutic itineraries of children after snakebites in the Brazilian Amazon: A thematic drawing-and-story study.PLoS neglected tropical diseases · 2025Article
- Treatment and treatment outcomes of snakebite envenoming in Uganda: a retrospective analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- Decentralization of snakebite antivenom treatment to indigenous community health centers in the Brazilian Amazon: From demand to the first treatment (the SAVING Program).PLoS neglected tropical diseases · 2025Article
- The Versatility of Serine Proteases from BrazilianBiomolecules · 2025Review
- SERPENT-Brasil: a technological tool for snakebite management.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Dermatopathological findings of Bothrops atrox snakebites: A case series in the Brazilian Amazon.PLoS neglected tropical diseases · 2024Article
- Snakebite Management: The Need of Reassessment, International Relations, and Effective Economic Measures to Reduce the Considerable SBE Burden.Journal of epidemiology and global health · 2024Review
- Development and validation of a minimum requirements checklist for snakebite envenoming treatment in the Brazilian Amazonia.PLoS neglected tropical diseases · 2024Article
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- Building an explanatory model for snakebite envenoming care in the Brazilian Amazon from the indigenous caregivers' perspective.PLoS neglected tropical diseases · 2023Article
- Multifaceted community health education programs as powerful tools to mitigate snakebite-induced deaths, disabilities, and socioeconomic burden.Toxicon: X · 2023Article
- Article
- Mapping of clinical management resources for snakebites and other animal envenomings in the Brazilian Amazon.Toxicon: X · 2022Article
- Bibliometric Analysis of Literature in Snake Venom-Related Research Worldwide (1933-2022).Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 4 institutions in 2 countries.
Funding
Abstract
Snakebite envenoming (SBE) is a neglected tropical disease with significant global morbidity and mortality. Even when antivenom is available in low-resource areas, health workers do not receive adequate training to manage SBEs. This study aims to develop and validate a clinical practice guideline (CPG) for SBE management across Brazil. A panel of expert judges with academic and/or technical expertise in SBE management performed content validation. The content validity index (CVI) score was 90% for CPG objectives, 89% for structure and presentation and 92% for relevance and classified the CPG as valid. A semantic validation was performed by analyzing focus group discussions with doctors and nurses from three municipalities of the Brazilian Amazon, after a 5-day meeting during which the CPG was presented. Two central themes emerged: knowledge acquired during the meeting and recommendations for improving the CPG. Based on these results, the CPG was revised into a final version. This study presents the successful development and validation process of a CPG for SBE management, which is targeted to a specific low-resource, high-burden setting. This development and validation process can be adapted to other settings and/or other neglected tropical diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.