Evidence map›Paper›PMID 35736931›Full record

ArticleToxics2022

Dioxin Congener Patterns in Breast Milk Samples from Areas Sprayed with Herbicide during the Vietnam War 40 Years after the War Ended.

Muneko Nishijo, Hoa Thi Vu, Tai Pham-The, Thao Ngoc Pham, Nghi Ngoc Tran, Hideaki Nakagawa, Hisao Nishijo

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Muneko NishijoDepartment of Public Health, Kanazawa Medical University, Uchinada 920-0293, Japan.
Hoa Thi VuDepartment of Public Health, Kanazawa Medical University, Uchinada 920-0293, Japan.
Tai Pham-TheBiomedical and Pharmaceutical Research Centre, Vietnam Military Medical University, Hanoi 12108, Vietnam.ORCID 0000-0002-5878-7307
Thao Ngoc PhamDepartment of Public Health, Kanazawa Medical University, Uchinada 920-0293, Japan.
Nghi Ngoc TranMinistry of Health, Vietnam Government, Hanoi 10060, Vietnam.
Hideaki NakagawaDepartment of Social and Environmental Medicine, Kanazawa Medical University, Uchinada 920-0293, Japan.
Hisao NishijoSystem Emotional Science, University of Toyama, Sugitani, Toyama 930-0194, Japan.ORCID 0000-0002-4786-4610
Kanazawa Medical University · JPMinistry of Health · VNUniversity of Toyama · JPVietnam Military Medical University · VN

Funding

Ministry of Education, Science, Sports and Culture Japan 17H04665
6 · The paper itself

Abstract

Large amounts of herbicides containing polychlorinated dibenzo-p-dioxins and dibenzo-furans (PCDD/Fs) were sprayed in South Vietnam during the Vietnam War. Levels of PCDD/Fs in the environment of South Vietnam remained high even 40 years later. A total of 861 breast milk samples (597 from three areas sprayed with herbicides, Quang Tri, Da Nang, and Bien Hoa, and 264 from three unsprayed areas in North Vietnam) were collected between 2007 and 2015 and the PCDD/F concentrations in the samples were determined. Levels of TEQ-PCDD/Fs and 17 PCDD/F congeners were higher in the sprayed area samples than the unsprayed area samples. We found particular PCDD/F congener patterns for different areas. High tetrachlorodibenzo-p-dioxin (TCDD) concentrations were found in Bien Hoa, high TCDD and 1,2,3,6,7,8-hexadibenzo-p-dioxin concentrations were found in Da Nang, and high 1,2,3,4,6,7,8-heptadibenzo-p-dioxin concentrations were found in Quan Tri. High 1,2,3,4,7,8-hexadibenzofuran and 1,2,3,4,6,7,8-heptadibenzofuran concentrations were also found in Da Nang and Quang Tri. However, breast feeding may have caused associations between the TCDD and polychlorinated dibenzofuran congener concentrations. Advanced statistical analysis will need to be performed in future to assess the characteristic PCDD/F congener profiles in breast milk samples from areas of Vietnam previously sprayed with herbicides.

Indexed as

breast milkcongener profiledioxinherbicideVietnam

Identifiers

PMID35736931
PMCPMC9227303
OpenAlexW4282832609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.