Evidence map›Paper›PMID 35736925›Full record

ArticleToxics2022

Lead and Cadmium Bioaccumulation in Fresh Cow's Milk in an Intermediate Area of the Central Andes of Peru and Risk to Human Health.

Doris Chirinos-Peinado, Jorge Castro-Bedriñana, Elva Ríos-Ríos, Gloria Mamani-Gamarra, Elías Quijada-Caro, Analí Huacho-Jurado, Wilfredo Nuñez-Rojas

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Doris Chirinos-PeinadoFood and Nutritional Security Research Centre, Universidad Nacional del Centro del Perú, Huancayo 12006, Peru.
Jorge Castro-BedriñanaFood and Nutritional Security Research Centre, Universidad Nacional del Centro del Perú, Huancayo 12006, Peru.ORCID 0000-0003-4312-6917
Elva Ríos-RíosFaculty of Science, Universidad Nacional Agraria La Molina, Lima 15024, Peru.
Gloria Mamani-GamarraMinistry of Production, Lima 15036, Peru.
Elías Quijada-CaroFaculty of Zootechnics, Universidad Nacional del Centro del Perú, Huancayo 12006, Peru.
Analí Huacho-JuradoFaculty of Zootechnics, Universidad Nacional del Centro del Perú, Huancayo 12006, Peru.
Wilfredo Nuñez-RojasSpecialized Research Institute, Faculty of Zootechnics, Universidad Nacional del Centro del Perú, Huancayo 12006, Peru.
Universidad Nacional del Centro del Perú · PEUniversidad Nacional Agraria La Molina · PE

Funding

Universidad Nacional del Centro del Perú Resolution N°2771-R-2019. Canon fund on canon and mining royalties
6 · The paper itself

Abstract

The dairy basin of the Mantaro River located in the centre of Peru faces serious anthropogenic disturbances as it receives emissions and discharges from the metallurgical mining activity located in the headwaters of the basin and milk contaminated with lead (Pb) and cadmium (Cd) endangers the environmental and human health, especially children. To measure the concentrations of Pb and Cd in milk and the dangers of their consumption in the Peruvian population, 40 milk samples were collected and quantified by atomic absorption spectrometry. The mean concentration of Pb in milk was 15 ± 2.6 µg/kg, which represented 75% of the Maximum Limit (ML), and that of Cd was 505 ± 123 µg/kg, which exceeded the ML by more than 194 times. The estimated weekly intake of Pb for people aged 2−85 years was below the Provisional Tolerable Weekly Intake (PTWI) references, determining risk coefficients (CRD) < 1. Weekly Cd intake was much higher than the PTWIs and CRDs were between 14 and 34, indicating that consumers would experience carcinogenic health effects, with children being at higher risk than adults, therefore, milk from the area is not safe for consumption. Cd would be transferred mainly through the soil (water)-grass-milk pathway, due to its presence in irrigation water and in fertilizers that contain Cd. The main pathway for Pb entry would be air-soil (water)-milk grass, from the fine particles emitted into the air by the mining-metallurgical activity, developed approximately 90 km from the study area.

Indexed as

cadmiumcontaminated milkdietary exposuredietary riskhazard indexleadtarget hazard quotient

Identifiers

PMID35736925
PMCPMC9227626
OpenAlexW4282559549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.