Evidence map›Paper›PMID 35736910›Full record

ArticleToxics2022

Biochemical and Metabolomic Responses of Antarctic Bacterium

Ziyi Cheng, Cuijuan Shi, Xiujun Gao, Xiaofei Wang, Guangfeng Kan

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ziyi ChengSchool of Marine Science and Technology, Harbin Institute of Technology, Huancui District, Weihai 264209, China.
Cuijuan ShiSchool of Marine Science and Technology, Harbin Institute of Technology, Huancui District, Weihai 264209, China.
Xiujun GaoSchool of Marine Science and Technology, Harbin Institute of Technology, Huancui District, Weihai 264209, China.
Xiaofei WangSchool of Marine Science and Technology, Harbin Institute of Technology, Huancui District, Weihai 264209, China.
Guangfeng KanSchool of Marine Science and Technology, Harbin Institute of Technology, Huancui District, Weihai 264209, China.
Harbin Institute of Technology · CN

Funding

Natural Scientific Research Innovation Foundation in Harbin Institute of Technology 2019KYCXJJYB17Shandong Provincial Natural Science Foundation, China ZR2021MC180
6 · The paper itself

Abstract

Heavy metal pollution in the Antarctic has gone beyond our imagination. Copper toxicity is a selective pressure on Planococcus sp. O5. We observed relatively broad tolerance in the polar bacterium. The heavy metal resistance pattern is Pb2+ > Cu2+ > Cd2+ > Hg2+ > Zn2+. In the study, we combined biochemical and metabolomics approaches to investigate the Cu2+ adaptation mechanisms of the Antarctic bacterium. Biochemical analysis revealed that copper treatment elevated the activity of antioxidants and enzymes, maintaining the bacterial redox state balance and normal cell division and growth. Metabolomics analysis demonstrated that fatty acids, amino acids, and carbohydrates played dominant roles in copper stress adaptation. The findings suggested that the adaptive mechanisms of strain O5 to copper stress included protein synthesis and repair, accumulation of organic permeable substances, up-regulation of energy metabolism, and the formation of fatty acids.

Indexed as

adaption responsesAntarctic straincopper stressmetabolomics

Identifiers

PMID35736910
PMCPMC9230899
OpenAlexW4281646590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.