Evidence map›Paper›PMID 35736873›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Visual Evaluation of Ultrafast MRI in the Assessment of Residual Breast Cancer after Neoadjuvant Systemic Therapy: A Preliminary Study Association with Subtype.

Maya Honda, Masako Kataoka, Mami Iima, Rie Ota, Akane Ohashi, Ayami Ohno Kishimoto, Kanae Kawai Miyake, Marcel Dominik Nickel, Yosuke Yamada, Masakazu Toi and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Institutional Variability in Ultrafast Breast MR Imaging: Comparing Compressed Sensing and View Sharing Techniques with Different Patient Populations and Contrast Injection Protocols.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  3. Abbreviated and Ultrafast Dynamic Contrast-enhanced (DCE) MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  4. Ultrafast Breast MRI: A Narrative Review.Journal of personalized medicine · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Maya HondaDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.ORCID 0000-0002-5337-3455
Masako KataokaDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.ORCID 0000-0002-6212-3351
Mami IimaDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.ORCID 0000-0002-1991-2494
Rie OtaDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.
Akane OhashiDepartment of Translational Medicine, Diagnostic Radiology, Lund University, Skåne University Hospital, 205-02 Malmo, Sweden.
Ayami Ohno KishimotoDepartment of Diagnostic Radiology, Kyoto Katsura Hospital, Yamadahirao-cho, Kyoto 615-8256, Japan.
Kanae Kawai MiyakeDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.ORCID 0000-0003-0793-9136
Marcel Dominik NickelMR Application Predevelopment, Siemens Healthcare GmbH, Allee am Roethelheimpark 2, 91052 Erlangen, Germany.
Yosuke YamadaDepartment of Diagnostic Pathology, Kyoto University Hospital, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.ORCID 0000-0001-7952-2706
Masakazu ToiDepartment of Breast Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.
Yuji NakamotoDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Kyoto 606-8507, Japan.
Kyoto University · JPKyoto Katsura Hospital · JPKyoto University Hospital · JPLund University · SESiemens Healthineers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the diagnostic performance of ultrafast dynamic contrast-enhanced (UF-DCE) MRI after the completion of neoadjuvant systemic therapy (NST) in breast cancer. In this study, MR examinations of 55 post-NST breast cancers were retrospectively analyzed. Residual tumor sizes were measured in the 20th phase of UF-DCE MRI, early and delayed phases of conventional dynamic contrast-enhanced (DCE) MRI, and high spatial-resolution contrast enhanced MRI (UF, early, delayed, and HR, respectively). The diagnostic performance for the detection of residual invasive cancer was calculated by receiver operating characteristic (ROC) analysis. The size difference between MRI and pathological findings was analyzed using the Wilcoxon signed-rank test with the Bonferroni correction. The overall area under the ROC curve (AUC) was highest for UF (0.86 and 0.88 for readers 1 and 2, respectively). The difference in imaging and pathological sizes for UF (5.7 ± 8.2 mm) was significantly smaller than those for early, delayed, and HR (p < 0.01). For luminal subtype breast cancer, the size difference was significantly smaller for UF and early than for delayed (p < 0.01). UF-DCE MRI demonstrated higher AUC and specificity for the more accurate detection of residual cancer and the visualization of tumor extent than conventional DCE MRI.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyContrast MediaFemaleHumansMagnetic Resonance ImagingNeoplasm, ResidualRetrospective StudiesContrast Mediabreast neoplasmmagnetic resonance imagingtreatment

Identifiers

PMID35736873
PMCPMC9230716
OpenAlexW4282550600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.