Evidence map›Paper›PMID 35736812›Full record

ArticleAnalytical chemistry2022

Human 2D Crypt Model for Assaying Intestinal Stem Cell Proliferation and Differentiation.

Yuli Wang, Christopher E Sims, Nancy L Allbritton

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. A Shared Framework for Gastrointestinal Organoid Research: It's Time.Cellular and molecular gastroenterology and hepatology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Synthetic photoresponsive hydrogels enableAdvanced functional materials · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Frontiers in bioengineering and biotechnology · 2024
    Article
  13. Article
  14. Recent Advances in Cell-Based In Vitro Models to Recreate Human Intestinal Inflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuli WangDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Christopher E SimsAltis Biosystems, Inc., Durham, North Carolina 27709, United States.
Nancy L AllbrittonDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-9242-768X
University of Washington · US

Funding

Development of a microphysiologic system to assay the interaction of the human colonic epithelium on Clostridium difficileR01DK120606 · NIDDK · UNIVERSITY OF WASHINGTON · PI ALLBRITTON, NANCY L., SHEIKH, SHEHZAD Z. · 2020 to 2023
$2.2M
A 2D Intestinal Crypt Platform for Compound ScreensR43DK130647 · NIDDK · ALTIS BIOSYSTEMS, INC. · PI BOAZAK, ELIZABETH, SIMS, CHRISTOPHER ELDRIDGE · 2021 to 2021
$257k
NIDDK NIH HHS R01 DK120606NIDDK NIH HHS R43 DK130647
6 · The paper itself

Abstract

Intestine is a common site of adverse drug effects in clinical trials; thus, improved

Indexed as

CollagenIntestinal MucosaAdultCell DifferentiationCell MovementCell ProliferationHumansCollagen

Identifiers

PMID35736812
PMCPMC9337237
OpenAlexW4283328502

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.