Evidence map›Paper›PMID 35736492›Full record

ReviewMetabolites2022

Lipid Peroxidation Produces a Diverse Mixture of Saturated and Unsaturated Aldehydes in Exhaled Breath That Can Serve as Biomarkers of Lung Cancer-A Review.

Saurin R Sutaria, Sadakatali S Gori, James D Morris, Zhenzhen Xie, Xiao-An Fu, Michael H Nantz

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Saurin R SutariaDepartment of Chemistry, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-2786-2511
Sadakatali S GoriDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
James D MorrisDepartment of Chemical Engineering, University of Louisville, Louisville, KY 40292, USA.
Zhenzhen XieDepartment of Chemical Engineering, University of Louisville, Louisville, KY 40292, USA.
Xiao-An FuDepartment of Chemical Engineering, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-6837-6512
Michael H NantzDepartment of Chemistry, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0003-1301-3399
University of Louisville · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The peroxidation of unsaturated fatty acids is a widely recognized metabolic process that creates a complex mixture of volatile organic compounds including aldehydes. Elevated levels of reactive oxygen species in cancer cells promote random lipid peroxidation, which leads to a variety of aldehydes. In the case of lung cancer, many of these volatile aldehydes are exhaled and are of interest as potential markers of the disease. Relevant studies reporting aldehydes in the exhaled breath of lung cancer patients were collected for this review by searching the PubMed and SciFinder

Indexed as

aldehydebiomarkerbreath analysisexhaled breathlipid peroxidationlung cancerunsaturatedVOC

Identifiers

PMID35736492
PMCPMC9229171
OpenAlexW4283118071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.