Evidence map›Paper›PMID 35736490›Full record

ArticleMetabolites2022

Metabolic Profiling of Bladder Cancer Patients' Serum Reveals Their Sensitivity to Neoadjuvant Chemotherapy.

Juntao Zhuang, Xiao Yang, Qi Zheng, Kai Li, Lingkai Cai, Hao Yu, Jiancheng Lv, Kexin Bai, Qiang Cao, Pengchao Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Metabolomic Signatures of Treatment Response in Bladder Cancer.International journal of molecular sciences · 2023
    Review
  7. Multiplatform untargeted metabolomics.Magnetic resonance in chemistry : MRC · 2023
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Juntao ZhuangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Xiao YangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Qi ZhengCenter of Molecular Metabolism, Nanjing University of Science and Technology, Nanjing 210094, China.
Kai LiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Lingkai CaiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Hao YuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jiancheng LvDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Kexin BaiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Qiang CaoDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Pengchao LiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Haiwei YangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Junsong WangCenter of Molecular Metabolism, Nanjing University of Science and Technology, Nanjing 210094, China.
Qiang LuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jiangsu Province Hospital · CNNanjing Medical University · CNNanjing University of Science and Technology · CN

Funding

National Natural Science Foundation of China 82072832; 81772711; 82073306
6 · The paper itself

Abstract

Numerous patients with muscle-invasive bladder cancer develop low responsiveness to cisplatin. Our purpose was to explore differential metabolites derived from serum in bladder cancer patients treated with neoadjuvant chemotherapy (NAC). Data of patients diagnosed with cT2-4aNxM0 was collected. Blood samples were retained prospectively before the first chemotherapy for untargeted metabolomics by

Indexed as

1H-NMRbladder cancermetabolomicsneoadjuvant chemotherapyserumUPLC-MS

Identifiers

PMID35736490
PMCPMC9229374
OpenAlexW4283019217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.