Evidence map›Paper›PMID 35736469›Full record

ArticleMetabolites2022

Using Mendelian Randomisation to Prioritise Candidate Maternal Metabolic Traits Influencing Offspring Birthweight.

Ciarrah-Jane Shannon Barry, Deborah A Lawlor, Chin Yang Shapland, Eleanor Sanderson, Maria Carolina Borges

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ciarrah-Jane Shannon BarryMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.ORCID 0000-0002-2088-0442
Deborah A LawlorMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.
Chin Yang ShaplandMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.ORCID 0000-0002-5797-1241
Eleanor SandersonMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.
Maria Carolina BorgesMRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.ORCID 0000-0001-7785-4547
University of Bristol · GB

Funding

British Heart Foundation AA/18/7/34219British Heart Foundation CH/F/20/90003European Research Council 101021566Medical Research Council MC_PC_17228Medical Research Council MC_PC_21038Medical Research Council MC_QA137853Medical Research Council MC_UU_00011/1Medical Research Council MC_UU_00011/1, MC_UU_00011/3, MC_UU_00011/6Medical Research Council MC_UU_00011/3Medical Research Council MC_UU_00011/6Medical Research Council MR/N024397/1Wellcome TrustWellcome Trust 218495/Z/19/Z
6 · The paper itself

Abstract

Marked physiological changes in pregnancy are essential to support foetal growth; however, evidence on the role of specific maternal metabolic traits from human studies is limited. We integrated Mendelian randomisation (MR) and metabolomics data to probe the effect of 46 maternal metabolic traits on offspring birthweight (

Indexed as

amino acidsbirthweightgeneticsglucoselipidsmaternalMendelian randomisationmetabolitesnuclear magnetic resonanceoffspring

Identifiers

PMID35736469
PMCPMC9231269
OpenAlexW4282568416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.