Evidence map›Paper›PMID 35736352›Full record

ReviewMedical sciences (Basel, Switzerland)2022

Valvular Heart Disease Epidemiology.

John Sukumar Aluru, Adam Barsouk, Kalyan Saginala, Prashanth Rawla, Alexander Barsouk

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06984172 (Effectiveness of Cardiac Rehabilitation With Remote Connection Device for Patients After Surgery for Acquired Heart Valve Disease), which is not on this map. Cited by 171 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed, 14 pooled it
46.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06984172 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of Cardiac Rehabilitation With Remote Connection Device for Patients After Surgery for Acquired Heart Valve Disease

TypeinterventionalSponsorHanoi Medical UniversityRan2025 to 2026Enrolled44ConditionsValvular DiseasesArmsRemote cardiac rehabilitation, Facility-based cardiac rehabilitation
3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 14 syntheses or guidelines pooled it, 297 citations in OpenAlex.

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  18. Biofidelic Simulations of the Ross Procedure: Arterial Growth and Remodeling in an Anatomical Context.International journal for numerical methods in biomedical engineering · 2026
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111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

John Sukumar AluruMinneapolis Heart Institute Foundation, Allina Health, Minneapolis, MN 55407, USA.
Adam BarsoukHillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Kalyan SaginalaPlains Regional Medical Group Internal Medicine, Clovis, NM 88101, USA.
Prashanth RawlaParrish Medical Center, Titusville, FL 32796, USA.ORCID 0000-0002-4361-8498
Alexander BarsoukAllegheny Health Network, Pittsburgh, PA 15212, USA.
Allegheny Health Network · USAllina Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valvular heart disease is a rapidly growing cause of global cardiovascular morbidity and mortality with diverse and evolving geographic distribution. The prevalence of rheumatic heart disease, the most common valvular heart disease (affecting approximately 41 million people), has been rising in developing nations, likely due to the expansion of the young adult population and the decrease in premature mortality that has resulted from improved access to antibiotics, microbiological testing, and echocardiography. Rheumatic heart disease has also been rising among the impoverished and, often, indigenous populations of developed nations, spurring public health initiatives that are aimed at alleviating healthcare disparities. Aortic valve stenotic disease is the most commonly occurring valvular pathology in developed nations (afflicting 9 million people worldwide) and its prevalence has been increasing with population aging and the increased prevalence of atherosclerosis. Aortic regurgitation is associated with diastolic, but not systolic, hypertension and it has likewise seen a rise in the developed world. Mitral regurgitation affects 24 million people worldwide, with great variability between and among nations. Primary mitral regurgitation arises as a consequence of myxomatous degeneration and mitral valve prolapse, which is largely due to genetic predispositions, while secondary mitral regurgitation accounts for 65% of cases and arises secondary to dilation and heart failure. Tricuspid regurgitation has become more prevalent in developed nations due to the increased usage of intracardiac pacemakers. Infective endocarditis prevalence has also grown in developed nations, likely due to population aging and the increased utilization of transcatheter valve replacement and prosthetic valves as interventions against the previously discussed valvular pathologies.

Indexed as

Heart Valve DiseasesMitral Valve InsufficiencyMitral Valve ProlapseRheumatic Heart DiseaseTricuspid Valve InsufficiencyHumansYoung Adultaortic regurgitationaortic valve stenotic diseaseepidemiologyinfective endocarditisrheumatic heart diseasetricuspid regurgitationvalvular heart disease

Identifiers

PMID35736352
PMCPMC9228968
OpenAlexW4283011955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.