Evidence map›Paper›PMID 35736206›Full record

ReviewMarine drugs2022

Algal Phlorotannins as Novel Antibacterial Agents with Reference to the Antioxidant Modulation: Current Advances and Future Directions.

Biswajita Pradhan, Rabindra Nayak, Prajna Paramita Bhuyan, Srimanta Patra, Chhandashree Behera, Sthitaprajna Sahoo, Jang-Seu Ki, Alessandra Quarta, Andrea Ragusa, Mrutyunjay Jena

Abstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Application of the brown macroalgaAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Effect of PelagicAnimals : an open access journal from MDPI · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Biswajita PradhanAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, India.ORCID 0000-0002-5410-7511
Rabindra NayakAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, India.ORCID 0000-0002-9060-4750
Prajna Paramita BhuyanDepartment of Botany, Maharaja Sriram Chandra Bhanja Deo University, Baripada 757003, Odisha, India.
Srimanta PatraCancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Rourkela 769008, Odisha, India.ORCID 0000-0002-0166-0903
Chhandashree BeheraAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, India.
Sthitaprajna SahooDepartment of Botany, Berhampur University, Berhampur 760007, Odisha, India.ORCID 0000-0001-8588-712X
Jang-Seu KiDepartment of Biotechnology, Sangmyung University, Seoul 03016, Korea.ORCID 0000-0002-6007-9262
Alessandra QuartaCNR-Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-1911-9864
Andrea RagusaCNR-Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-2198-6185
Mrutyunjay JenaAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, India.ORCID 0000-0003-2157-4292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing drug resistance of infectious microorganisms is considered a primary concern of global health care. The screening and identification of natural compounds with antibacterial properties have gained immense popularity in recent times. It has previously been shown that several bioactive compounds derived from marine algae exhibit antibacterial activity. Similarly, polyphenolic compounds are generally known to possess promising antibacterial capacity, among other capacities. Phlorotannins (PTs), an important group of algae-derived polyphenolic compounds, have been considered potent antibacterial agents both as single drug entities and in combination with commercially available antibacterial drugs. In this context, this article reviews the antibacterial properties of polyphenols in brown algae, with particular reference to PTs. Cell death through various molecular modes of action and the specific inhibition of biofilm formation by PTs were the key discussion of this review. The synergy between drugs was also discussed in light of the potential use of PTs as adjuvants in the pharmacological antibacterial treatment.

Indexed as

AntioxidantsPhaeophyceaeAnti-Bacterial AgentsPolyphenolsTanninsAnti-Bacterial AgentsAntioxidantsPolyphenolsTanninsantibacterial activityantibioticantioxidantbrown algaemarine algaephlorotanninpolyphenols

Identifiers

PMID35736206
PMCPMC9228090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.