Evidence map›Paper›PMID 35736166›Full record

ReviewMarine drugs2022

The Immune System of Marine Organisms as Source for Drugs against Infectious Diseases.

Alberto Falco, Mikolaj Adamek, Patricia Pereiro, David Hoole, José Antonio Encinar, Beatriz Novoa, Ricardo Mallavia

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Alberto FalcoInstitute of Research, Development, and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0001-7726-6577
Mikolaj AdamekFish Disease Research Unit, Institute for Parasitology, University of Veterinary Medicine, 30559 Hannover, Germany.ORCID 0000-0003-4890-3164
Patricia PereiroInstitute of Marine Research, Consejo Superior de Investigaciones Científicas (IIM-CSIC), 36208 Vigo, Spain.ORCID 0000-0002-8734-3334
David HooleSchool of Life Sciences, Keele University, Keele ST5 5BG, UK.
José Antonio EncinarInstitute of Research, Development, and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0002-7219-3863
Beatriz NovoaInstitute of Marine Research, Consejo Superior de Investigaciones Científicas (IIM-CSIC), 36208 Vigo, Spain.ORCID 0000-0003-4888-8419
Ricardo MallaviaInstitute of Research, Development, and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0001-8058-1009
Universitat de Miguel Hernández d'Elx · ESConsejo Superior de Investigaciones Científicas · ESKeele University · GBUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) 426513195MCIN/AEI/10.13039/501100011033 and by "ERDF A way of making Europe" RTI2018-101969-J-I00Ministry of Agriculture, Fisheries and Food (MAPA) and European Maritime, Fisheries and Aq-uaculture Fund (EMFAF) MetDisFish
6 · The paper itself

Abstract

The high proliferation of microorganisms in aquatic environments has allowed their coevolution for billions of years with other living beings that also inhabit these niches. Among the different existing types of interaction, the eternal competition for supremacy between the susceptible species and their pathogens has selected, as part of the effector division of the immune system of the former ones, a vast and varied arsenal of efficient antimicrobial molecules, which is highly amplified by the broad biodiversity radiated, above any others, at the marine habitats. At present, the great recent scientific and technological advances already allow the massive discovery and exploitation of these defense compounds for therapeutic purposes against infectious diseases of our interest. Among them, antimicrobial peptides and antimicrobial metabolites stand out because of the wide dimensions of their structural diversities, mechanisms of action, and target pathogen ranges. This revision work contextualizes the research in this field and serves as a presentation and scope identification of the Special Issue from

Indexed as

Anti-Infective AgentsCommunicable DiseasesAnti-Bacterial AgentsAquatic OrganismsHumansImmune SystemAnti-Bacterial AgentsAnti-Infective Agentsantimicrobial drug discoveryantimicrobial metabolitesantimicrobial peptidesinnate immune system

Identifiers

PMID35736166
PMCPMC9230875
OpenAlexW4281702706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.