Evidence map›Paper›PMID 35736159›Full record

ArticleMarine drugs2022

A Novel Bi-Functional Fibrinolytic Enzyme with Anticoagulant and Thrombolytic Activities from a Marine-Derived Fungus

Lihong Zhao, Xiuping Lin, Jingyun Fu, Jun Zhang, Wei Tang, Zengguo He

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Dihydrogeodin fromMarine drugs · 2025
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  10. Hemostatically Active Proteinase Produced byInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. MarineMarine drugs · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lihong ZhaoSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-4343-0038
Xiuping LinCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Jingyun FuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Jun ZhangSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Wei TangSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Zengguo HeSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Ocean University of China · CNChinese Academy of Sciences · CNMarine Biomedical Research Institute of Qingdao · CN

Funding

Science and Technology Projects in Key areas of Guangdong 2020B0202010001
6 · The paper itself

Abstract

Fibrinolytic enzymes are important components in the treatment of thrombosis-associated disorders. A new bi-functional fibrinolytic enzyme, versiase, was identified from a marine-derived fungus

Indexed as

AnticoagulantsProteomicsAspergillusFibrinFibrinolytic AgentsFungiHydrogen-Ion ConcentrationMetalloproteasesMolecular WeightTemperatureAnticoagulantsFibrinFibrinolytic AgentsMetalloproteasesanticoagulant activityA. versicolor ZLH-1fibrinolytic enzymethrombolytic activity

Identifiers

PMID35736159
PMCPMC9229710
OpenAlexW4281689218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.