Evidence map›Paper›PMID 35736155›Full record

ReviewMarine drugs2022

Marine Microbial-Derived Resource Exploration: Uncovering the Hidden Potential of Marine Carotenoids.

Ray Steven, Zalfa Humaira, Yosua Natanael, Fenny M Dwivany, Joko P Trinugroho, Ari Dwijayanti, Tati Kristianti, Trina Ekawati Tallei, Talha Bin Emran, Heewon Jeon and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
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  12. Article
  13. Sun protection and antibacterial activities of carotenoids from the soft coralSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Ray StevenInstitut Teknologi Bandung, School of Life Sciences and Technology, Bandung 40132, Indonesia.ORCID 0000-0001-9877-225X
Zalfa HumairaInstitut Teknologi Bandung, School of Life Sciences and Technology, Bandung 40132, Indonesia.
Yosua NatanaelInstitut Teknologi Bandung, School of Life Sciences and Technology, Bandung 40132, Indonesia.
Fenny M DwivanyInstitut Teknologi Bandung, School of Life Sciences and Technology, Bandung 40132, Indonesia.ORCID 0000-0001-6895-3914
Joko P TrinugrohoDepartment of Life Sciences, Imperial College London, South Kensington Campus, London SW72AZ, UK.ORCID 0000-0003-0343-3402
Ari DwijayantiCNRS@CREATE Ltd., 1 Create Way, #08-01 Create Tower, Singapore 138602, Singapore.
Tati KristiantiInstitut Pendidikan Indonesia, Garut 44151, Indonesia.
Trina Ekawati TalleiDepartment of Biology, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Manado 95115, Indonesia.ORCID 0000-0002-7963-7527
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Heewon JeonDepartment of Pathology, College of Korean Medicine, Kyung Hee University, 1-5 Hoegidong, Seoul 02447, Korea.
Fahad A AlhumaydhiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 52571, Saudi Arabia.ORCID 0000-0002-0151-8309
Ocky Karna RadjasaOceanography Research Center, The Earth Sciences and Maritime Research Organization, National Research and Innovation Agency, North Jakarta 14430, Indonesia.
Bonglee KimDepartment of Pathology, College of Korean Medicine, Kyung Hee University, 1-5 Hoegidong, Seoul 02447, Korea.ORCID 0000-0002-8678-156X
Bandung Institute of Technology · IDKyung Hee University · KRDaffodil International University · BDImperial College London · GBIndonesia University of Education · IDNational Research and Innovation Agency · IDQassim University · SASam Ratulangi University · ID

Funding

2016 SETAC Asia/Pacific ConferenceR13ES027302 · NIEHS · SOCIETY/ENVIRONMENTAL TOXICOLOGY/CHEM · PI MENZIE, CHARLES · 2016 to 2016
$6k
Korea Health Industry Development Institute HF20C0038Korea Health Industry Development Institute HF20C0116National Research Foundation of Korea No. 2020R1A5A2019413National Research Foundation of Korea NRF-2020R1I1A2066868NIEHS NIH HHS 27302C0038
6 · The paper itself

Abstract

Microbes in marine ecosystems are known to produce secondary metabolites. One of which are carotenoids, which have numerous industrial applications, hence their demand will continue to grow. This review highlights the recent research on natural carotenoids produced by marine microorganisms. We discuss the most recent screening approaches for discovering carotenoids, using in vitro methods such as culture-dependent and culture-independent screening, as well as in silico methods, using secondary metabolite Biosynthetic Gene Clusters (smBGCs), which involves the use of various rule-based and machine-learning-based bioinformatics tools. Following that, various carotenoids are addressed, along with their biological activities and metabolic processes involved in carotenoids biosynthesis. Finally, we cover the application of carotenoids in health and pharmaceutical industries, current carotenoids production system, and potential use of synthetic biology in carotenoids production.

Indexed as

CarotenoidsEcosystemComputational BiologyMultigene FamilySynthetic BiologyCarotenoidsbiosynthetic gene clustercarotenoidsmarinemicroorganisms

Identifiers

PMID35736155
PMCPMC9229179
OpenAlexW4281989509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.