Evidence map›Paper›PMID 35736125›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

The Antidepressant Sertraline Induces the Formation of Supersized Lipid Droplets in the Human Pathogen

Matthew R Breuer, Ananya Dasgupta, Joseph G Vasselli, Xiaorong Lin, Brian D Shaw, Matthew S Sachs

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Drug Discovery and Repurposing forJournal of fungi (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Whole-chromosome duplications drive antimicrobial resistance inbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Searching for new antifungals for the treatment of cryptococcosis.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Matthew R BreuerDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.
Ananya DasguptaDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.
Joseph G VasselliDepartment of Plant Pathology and Microbiology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-6294-239X
Xiaorong LinDepartment of Microbiology, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-3390-8387
Brian D ShawDepartment of Plant Pathology and Microbiology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-1828-0963
Matthew S SachsDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-9891-9223
Texas A&M University · USUniversity of Georgia · US

Funding

Determining genetic signatures of the cryptococcal response to Zoloft by an integrated approach combining transcriptome, translatome and genetic screensR21AI138158 · NIAID · TEXAS A&M UNIVERSITY · PI LIN, XIAORONG, SACHS, MATTHEW STEVEN · 2018 to 2019
$395k
NIAID NIH HHS R21 AI138158NIH HHS R21AI138158
6 · The paper itself

Abstract

The prevalence and increasing incidence of fungal infections globally is a significant worldwide health problem. Cryptococcosis, primarily caused by the pathogenic yeast

Indexed as

antifungal therapyAspergillus fumigatusCandida albicansCryptococcus neoformanslipid dropletsSaccharomyces cerevisiae

Identifiers

PMID35736125
PMCPMC9224953
OpenAlexW4283032347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.