Evidence map›Paper›PMID 35736043›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Antiproliferative and Cytotoxic Cytochalasins from

Katherine Yasmin M Garcia, Mark Tristan J Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E B Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cytochalasins from the Ash Endophytic FungusMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Globospiramine fromCells · 2024
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Katherine Yasmin M GarciaThe Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0002-3057-0413
Mark Tristan J QuimqueThe Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.
Christopher LambertDepartment of Microbial Drugs, Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF), Partner Site Hannover/Braunschweig, Inhoffenstraße 7, 38124 Braunschweig, Germany.ORCID 0000-0002-1899-8214
Katharina SchmidtDepartment of Cell Biology, Helmholtz Centre for Infection Research (HZI), Inhoffenstraße 7, 38124 Braunschweig, Germany.
Gian PrimahanaDepartment of Microbial Drugs, Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF), Partner Site Hannover/Braunschweig, Inhoffenstraße 7, 38124 Braunschweig, Germany.ORCID 0000-0001-8176-3859
Theresia E B StradalDepartment of Cell Biology, Helmholtz Centre for Infection Research (HZI), Inhoffenstraße 7, 38124 Braunschweig, Germany.
Andreas RatzenböckInstitut für Organische Chemie, Universität Regensburg, Universitätstrasse 31, 93053 Regensburg, Germany.ORCID 0000-0001-5088-1721
Hans-Martin DahseLeibniz-Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany.
Chayanard PhukhamsakdaCenter of Excellence in Fungal Research, Mae Fah Luang University, Chiang Rai 57100, Thailand.ORCID 0000-0002-1033-937X
Marc StadlerDepartment of Microbial Drugs, Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF), Partner Site Hannover/Braunschweig, Inhoffenstraße 7, 38124 Braunschweig, Germany.ORCID 0000-0002-7284-8671
Frank SurupDepartment of Microbial Drugs, Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF), Partner Site Hannover/Braunschweig, Inhoffenstraße 7, 38124 Braunschweig, Germany.ORCID 0000-0001-5234-8525
Allan Patrick G MacabeoLaboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for the Natural and Applied Sciences, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0001-7972-106X
Helmholtz Centre for Infection Research · DEUniversity of Santo Tomas · PHLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEMae Fah Luang University · THMindanao State University – Iligan Institute of Technology · PHUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laying the groundwork on preliminary structure-activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fungus,

Indexed as

actin inhibitorsantiproliferativecytotoxicECD–TDDFTSparticola triseptatastructure elucidation

Identifiers

PMID35736043
PMCPMC9225350
OpenAlexW4281477460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.