Evidence map›Paper›PMID 35735748›Full record

ArticlemSystems2022

Differential Binding of Carbapenems with the AdeABC Efflux Pump and Modulation of the Expression of AdeB Linked to Novel Mutations within Two-Component System AdeRS in Carbapenem-Resistant Acinetobacter baumannii.

Subhasree Roy, Vivek Junghare, Shanta Dutta, Saugata Hazra, Sulagna Basu

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Carbapenem-ResistantMicroorganisms · 2025
    Review
  9. Article
  10. Review
  11. Clonal dissemination of carbapenem-resistant ST477Frontiers in cellular and infection microbiology · 2025
    Article
  12. Carbapenem-resistantiScience · 2024
    Review
  13. The mobilome landscape of biocide-resistance in Brazilian ESKAPE isolates.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  14. Epidemiology, resistance genomics and susceptibility ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Alteration ofMicrobiology spectrum · 2023
    Article
  19. Efflux-Related Carbapenem Resistance inInternational journal of molecular sciences · 2023
    Article
  20. Role of EmaSR in Ethanol Metabolism byInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Subhasree Roy *Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.
Vivek Junghare *Department of Bioscience and Bioengineering, Indian Institute of Technology Roorkee (IITR), Roorkee, Uttarakhand, India.
Shanta DuttaDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.
Saugata Hazra *Department of Bioscience and Bioengineering, Indian Institute of Technology Roorkee (IITR), Roorkee, Uttarakhand, India.ORCID 0000-0002-3074-1534
Sulagna BasuDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.ORCID 0000-0002-7811-7140
National Institute of Cholera and Enteric Diseases · INIndian Institute of Technology Roorkee · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance-nodulation-division-type efflux system AdeABC plays an important role in carbapenem resistance among Acinetobacter baumannii. However, a knowledge gap is observed regarding the role of its regulator AdeRS in carbapenem-resistant A. baumannii (CRAB). This study effectively combines microbiological analysis with an

Indexed as

Acinetobacter baumanniiCarbapenemsAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsMolecular Docking SimulationMutationAnti-Bacterial AgentsBacterial ProteinsCarbapenemsMembrane Transport Proteins3D modelingAcinetobacter baumanniiAdeABCAdeRSantimicrobial resistancecarbapenem resistanceIndiamolecular dockingneonatal sepsisPAßN

Identifiers

PMID35735748
PMCPMC9426577
OpenAlexW4283330673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.