Evidence map›Paper›PMID 35735711›Full record

ArticleGels (Basel, Switzerland)2022

Facile Fabrication of Transparent and Opaque Albumin Methacryloyl Gels with Highly Improved Mechanical Properties and Controlled Pore Structures.

Mengdie Xu, Nabila Mehwish, Bae Hoon Lee

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. UV-Crosslinked Poly(Gels (Basel, Switzerland) · 2023
    Article
  5. Toward Tunable Protein-Driven Hydrogel Lens.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Hydrogels for the treatment of rheumatoid arthritis.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mengdie XuWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325011, China.
Nabila MehwishWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325011, China.ORCID 0000-0002-3779-8293
Bae Hoon LeeWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325011, China.ORCID 0000-0002-7222-0008
University of Chinese Academy of Sciences · CNZhejiang Lab · CN

Funding

Basic scientific research projects Foundation in Wenzhou Y202018National Natural Science Foundation of China 32171316Wenzhou Institute, University of Chinese Academy of Sciences WIUCASQD2019003Zhejiang Provincial Natural Science Foundation LGF19E030001
6 · The paper itself

Abstract

For porous protein scaffolds to be employed in tissue-engineered structures, the development of cost-effective, macroporous, and mechanically improved protein-based hydrogels, without compromising the original properties of native protein, is crucial. Here, we introduced a facile method of albumin methacryloyl transparent hydrogels and opaque cryogels with adjustable porosity and improved mechanical characteristics via controlling polymerization temperatures (room temperature and -80 °C). The structural, morphological, mechanical, and physical characteristics of both porous albumin methacryloyl biomaterials were investigated using FTIR, CD, SEM, XRD, compression tests, TGA, and swelling behavior. The biodegradation and biocompatibility of the various gels were also carefully examined. Albumin methacryloyl opaque cryogels outperformed their counterpart transparent hydrogels in terms of mechanical characteristics and interconnecting macropores. Both materials demonstrated high mineralization potential as well as good cell compatibility. The solvation and phase separation owing to ice crystal formation during polymerization are attributed to the transparency of hydrogels and opacity of cryogels, respectively, suggesting that two fully protein-based hydrogels could be used as visible detectors/sensors in medical devices or bone regeneration scaffolds in the future.

Indexed as

bovine serum albumin methacryloylcryogelshydrogelsmechanical propertiesporous biomaterials

Identifiers

PMID35735711
PMCPMC9222780
OpenAlexW4281735554

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.