Evidence map›Paper›PMID 35735678›Full record

ReviewGels (Basel, Switzerland)2022

Insights into the Role of Biopolymer-Based Xerogels in Biomedical Applications.

H P S Abdul Khalil, Esam Bashir Yahya, Husnul Azan Tajarudin, Venugopal Balakrishnan, Halimatuddahliana Nasution

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Immobilization of crude cellulase from Aspergillus foetidus on agar xerogel and its application for carrot juice extraction.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Current Challenges and Opportunities for Improved Cannabidiol Solubility.International journal of molecular sciences · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H P S Abdul KhalilSchool of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0003-2403-809X
Esam Bashir YahyaSchool of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0002-1599-1754
Husnul Azan TajarudinSchool of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0001-7878-6072
Venugopal BalakrishnanInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0002-4874-600X
Halimatuddahliana NasutionDepartment of Chemical Engineering, Faculty of Engineering, Universitas Sumatera Utara, Medan 20155, Indonesia.

Funding

Ministry of Higher Education Malaysia for Fundamental Research Grant Scheme-Malaysia Re-search Star Award (FRGS-MRSA) FRGS/1/2019/TK05/USM/01/6
6 · The paper itself

Abstract

Xerogels are advanced, functional, porous materials consisting of ambient, dried, cross-linked polymeric networks. They possess characteristics such as high porosity, great surface area, and an affordable preparation route; they can be prepared from several organic and inorganic precursors for numerous applications. Owing to their desired properties, these materials were found to be suitable for several medical and biomedical applications; the high drug-loading capacity of xerogels and their ability to maintain sustained drug release make them highly desirable for drug delivery applications. As biopolymers and chemical-free materials, they have been also utilized in tissue engineering and regenerative medicine due to their high biocompatibility, non-immunogenicity, and non-cytotoxicity. Biopolymers have the ability to interact, cross-link, and/or trap several active agents, such as antibiotic or natural antimicrobial substances, which is useful in wound dressing and healing applications, and they can also be used to trap antibodies, enzymes, and cells for biosensing and monitoring applications. This review presents, for the first time, an introduction to biopolymeric xerogels, their fabrication approach, and their properties. We present the biological properties that make these materials suitable for many biomedical applications and discuss the most recent works regarding their applications, including drug delivery, wound healing and dressing, tissue scaffolding, and biosensing.

Indexed as

biomedical applicationsbiopolymersdried gelsporous materialsxerogel

Identifiers

PMID35735678
PMCPMC9222565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.