Evidence map›Paper›PMID 35735664›Full record

ArticleClinics and practice2022

The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population.

Evgenia Lymperaki, Evangelia Stalika, George Tzavelas, Efthymia Tormpantoni, Diana Samara, Eleni Vagdatli, Ioannis Tsamesidis

Open access · goldAbstract read
In one paragraph

Article in Clinics and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Evgenia LymperakiDepartment of Biomedical Sciences, International Hellenic University, 57001 Thessaloniki, Greece.
Evangelia StalikaLab of Computing and Medical Informatics, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
George TzavelasDepartment of Statistics and Insurance Science, University of Piraeus, 18534 Piraeus, Greece.
Efthymia TormpantoniBlood Bank Section, Naousa General Hospital, 59200 Naousa, Greece.
Diana SamaraBlood Bank Section, Naousa General Hospital, 59200 Naousa, Greece.
Eleni VagdatliLaboratory of Biopathology, Hippokratio General Hospital, 54642 Thessaloniki, Greece.
Ioannis TsamesidisDepartment of Biomedical Sciences, International Hellenic University, 57001 Thessaloniki, Greece.ORCID 0000-0002-1439-3920
International Hellenic University · GRWestern Attica General Hospital · GRAristotle University of Thessaloniki · GRIppokrateio General Hospital of Thessaloniki · GRUniversity of Piraeus · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study is to further highlight the differences between different ABO blood groups and Rhesus types with health biomarkers.

methodsIn total 150 active healthy blood donors participated in our study comprising of 80 males from 19-61 years and 70 females aged from 21 to 64. Participants carrying blood group A were 55 individuals, blood group B 32, blood group O 51, and blood group AB 12, RHD+ 132, and RHD- 18. All the volunteer regular blood donors were selected recognizing them as a healthy population excluding drug and supplements intake. Their blood samples were analyzed just before blood donation for biochemical, hematological, and antioxidant markers. Statistical computations were performed using the SPSS tool, specifically, the one-way ANOVA test, Chi-square statistics, and logistic regression were used as statistical models.

resultsO blood donors presented better iron absorption and the worst lipid profile. Indeed, a significant trend of high atheromatic index values revealed an increased risk for hyperlipidemia, in contrast with blood group A presenting a better lipid profile with lower atheromatic index values. There was also a gender related association for blood group A compared with O that was further highlighted using binary logistic regression.

conclusionIn this study, a significant difference was observed among the ABO blood groups in several of the examined biochemical and hematological biomarkers. O blood group appeared different behavior in comparison to all the tested blood groups and furthermore the RHD-group presented a better lipid profile in comparison to the RHD+ group. In order to obtain a more comprehensive view of the correlation between the ABO blood group and biochemical markers, further studies are required.

Indexed as

ABO blood systematheromatic indexhealth biomarkerslipid profileRhesus typetotal antioxidant status

Identifiers

PMID35735664
PMCPMC9221977
OpenAlexW4281669329

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.