Evidence map›Paper›PMID 35735607›Full record

ArticleCurrent issues in molecular biology2022

miR-92a-2-5p Regulates the Proliferation and Differentiation of ASD-Derived Neural Progenitor Cells.

Wenting Zhuang, Hui Liu, Zhize He, Jielan Ju, Qiuxia Gao, Zhiyan Shan, Lei Lei

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wenting ZhuangDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Hui LiuDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Zhize HeDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Jielan JuDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Qiuxia GaoDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Zhiyan ShanDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Lei LeiDepartment of Histology and Embryology, Harbin Medical University, Harbin 150000, China.
Harbin Medical University · CN

Funding

Key projects of Heilongjiang Natural Science Foundation ZD2021C005
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with abnormal behavior. However, the pathogenesis of ASD remains to be clarified. It has been demonstrated that miRNAs are essential regulators of ASD. However, it is still unclear how miR-92a-2-5p acts on the developing brain and the cell types directly. In this study, we used neural progenitor cells (NPCs) derived from ASD-hiPSCs as well as from neurotypical controls to examine the effects of miR-92a-2-5p on ASD-NPCs proliferation and neuronal differentiation, and whether miR-92a-2-5p could interact with genetic risk factor,

Indexed as

ASDdifferentiationDLG3miR-92a-2-5pneural precursor cellsproliferation

Identifiers

PMID35735607
PMCPMC9222067
OpenAlexW4281550348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.