Evidence map›Paper›PMID 35735568›Full record

ArticleBiosensors2022

The Integration of Gold Nanoparticles with Polymerase Chain Reaction for Constructing Colorimetric Sensing Platforms for Detection of Health-Related DNA and Proteins.

Wanhe Wang, Xueliang Wang, Jingqi Liu, Chuankai Lin, Jianhua Liu, Jing Wang

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Molecular detection and phylogenetic analysis ofVeterinary research forum : an international quarterly journal · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wanhe WangInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Xueliang WangInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Jingqi LiuInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Chuankai LinInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Jianhua LiuInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Jing WangInstitute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.ORCID 0000-0001-7104-6661

Funding

National Natural Science Foundation of China 2210011340
6 · The paper itself

Abstract

Polymerase chain reaction (PCR) is the standard tool in genetic information analysis, and the desirable detection merits of PCR have been extended to disease-related protein analysis. Recently, the combination of PCR and gold nanoparticles (AuNPs) to construct colorimetric sensing platforms has received considerable attention due to its high sensitivity, visual detection, capability for on-site detection, and low cost. However, it lacks a related review to summarize and discuss the advances in this area. This perspective gives an overview of established methods based on the combination of PCR and AuNPs for the visual detection of health-related DNA and proteins. Moreover, this work also addresses the future trends and perspectives for PCR-AuNP hybrid biosensors.

Indexed as

GoldMetal NanoparticlesColorimetryDNAPolymerase Chain ReactionProteinsDNAGoldProteinsAuNPscolorimetric detectionDNAPCRproteins

Identifiers

PMID35735568
PMCPMC9220820

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.