Evidence map›Paper›PMID 35735546›Full record

ArticleBiosensors2022

Compact Smartphone-Based Laser Speckle Contrast Imaging Endoscope Device for Point-of-Care Blood Flow Monitoring.

Youngkyu Kim, Woo June Choi, Jungmin Oh, Jun Ki Kim

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Recent Progress in Blood Flow Sensing.Sensors and actuators. A, Physical · 2025
    Article
  4. Article
  5. Imaging-Navigated Surgery.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Youngkyu KimBiomedical Engineering Research Center, Asan Institute for Life Science, Asan Medical Center, Seoul 05505, Korea.ORCID 0000-0002-9595-1962
Woo June ChoiSchool of Electrical and Electronics Engineering, Chung-Ang University, Seoul 06974, Korea.ORCID 0000-0003-0793-2735
Jungmin OhBiomedical Engineering Research Center, Asan Institute for Life Science, Asan Medical Center, Seoul 05505, Korea.ORCID 0000-0002-9304-3346
Jun Ki KimBiomedical Engineering Research Center, Asan Institute for Life Science, Asan Medical Center, Seoul 05505, Korea.ORCID 0000-0002-0099-9681
Asan Medical Center · KRChung-Ang University · KR

Funding

Ministry of Health and Welfare HI18C2391Ministry of Trade, Industry and Energy 20000843National Research Foundation of Korea 2020R1F1A1072912, 2019R1A2C2084122, 2020R1A5A1018052, 2018R1A5A2020732
6 · The paper itself

Abstract

Laser speckle contrast imaging (LSCI) is a powerful visualization tool for quantifying blood flow in tissues, providing simplicity of configuration, ease of use, and intuitive results. With recent advancements, smartphone and camera technologies are suitable for the development of smartphone-based LSCI applications for point-of-care (POC) diagnosis. A smartphone-based portable LSCI endoscope system was validated for POC diagnosis of vascular disorders. The endoscope consisted of compact LED and laser illumination, imaging optics, and a flexible fiberscope assembled in a 3D-printed hand-held cartridge for access to body cavities and organs. A smartphone's rear camera was mounted thereto, enabling endoscopy, LSCI image acquisition, and processing. Blood flow imaging was calibrated in a perfused tissue phantom consisting of a microparticle solution pumped at known rates through tissue-mimicking gel and validated in a live rat model of BBN-induced bladder cancer. Raw LSCI images successfully visualized phantom flow: speckle flow index showed linearity with the pump flow rate. In the rat model, healthy and cancerous bladders were distinguishable in structure and vasculature. The smartphone-based low-cost portable mobile endoscope for monitoring blood flow and perfusion shows promise for preclinical applications and may be suitable for primary diagnosis at home or as a cost-effective POC testing assay.

Indexed as

Laser Speckle Contrast ImagingPoint-of-Care SystemsSmartphoneAnimalsEndoscopesPhantoms, ImagingRatsRegional Blood FlowUrinary Bladder NeoplasmsVascular Diseasesblood flowendoscopylaser speckle contrast imagingpoint of caresmartphone

Identifiers

PMID35735546
PMCPMC9220785
OpenAlexW4281732365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.