Evidence map›Paper›PMID 35735504›Full record

ArticleBioengineering (Basel, Switzerland)2022

BM-Net: CNN-Based MobileNet-V3 and Bilinear Structure for Breast Cancer Detection in Whole Slide Images.

Jin Huang, Liye Mei, Mengping Long, Yiqiang Liu, Wei Sun, Xiaoxiao Li, Hui Shen, Fuling Zhou, Xiaolan Ruan, Du Wang and 3 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. A Survey of Convolutional Neural Network in Breast Cancer.Computer modeling in engineering & sciences : CMES · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jin HuangThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.
Liye MeiThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0002-2555-9199
Mengping LongThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.
Yiqiang LiuDepartment of Pathology, Peking University Cancer Hospital, Beijing 100142, China.ORCID 0000-0002-7239-2360
Wei SunDepartment of Pathology, Peking University Cancer Hospital, Beijing 100142, China.
Xiaoxiao LiThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.
Hui ShenThe Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
Fuling ZhouThe Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
Xiaolan RuanDepartment of Hematology, Renmin Hospital, Wuhan University, Wuhan 430071, China.
Du WangThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0002-0098-7613
Shu WangDepartment of Breast Surgery, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-8651-4795
Taobo HuThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0001-5124-7167
Cheng LeiThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.

Funding

2020 Medical Science and Technology Innovation Platform Support Project of Zhongnan Hospi-tal of Wuhan University lcyf202010National Natural Science Foundation of China 61905182National Natural Science Foundation of China 62075200National Natural Science Foundation of China 82002979Science Fund for Distinguished Young Scholars of Hubei Province 2021CFA042The Key Research and Development Program of Hubei province 2020BAB005Wuhan Research Program of Application Foundation and Advanced Technology 2020020601012237
6 · The paper itself

Abstract

Breast cancer is one of the most common types of cancer and is the leading cause of cancer-related death. Diagnosis of breast cancer is based on the evaluation of pathology slides. In the era of digital pathology, these slides can be converted into digital whole slide images (WSIs) for further analysis. However, due to their sheer size, digital WSIs diagnoses are time consuming and challenging. In this study, we present a lightweight architecture that consists of a bilinear structure and MobileNet-V3 network, bilinear MobileNet-V3 (BM-Net), to analyze breast cancer WSIs. We utilized the WSI dataset from the ICIAR2018 Grand Challenge on Breast Cancer Histology Images (BACH) competition, which contains four classes: normal, benign, in situ carcinoma, and invasive carcinoma. We adopted data augmentation techniques to increase diversity and utilized focal loss to remove class imbalance. We achieved high performance, with 0.88 accuracy in patch classification and an average 0.71 score, which surpassed state-of-the-art models. Our BM-Net shows great potential in detecting cancer in WSIs and is a promising clinical tool.

Indexed as

bilinear structurebreast cancer detectionlightweightMobileNet-V3whole slide image

Identifiers

PMID35735504
PMCPMC9220285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.