Evidence map›Paper›PMID 35735445›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Artificial Intelligence System for Predicting Prostate Cancer Lesions from Shear Wave Elastography Measurements.

Ciprian Cosmin Secasan, Darian Onchis, Razvan Bardan, Alin Cumpanas, Dorin Novacescu, Corina Botoca, Alis Dema, Ioan Sporea

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. TRUSformer: improving prostate cancer detection from micro-ultrasound using attention and self-supervision.International journal of computer assisted radiology and surgery · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ciprian Cosmin SecasanDepartment of Urology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-1928-7809
Darian OnchisDepartment of Computer Science, West University, 300223 Timisoara, Romania.
Razvan BardanDepartment of Urology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-8288-5468
Alin CumpanasDepartment of Urology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Dorin NovacescuDepartment of Urology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-2520-7636
Corina BotocaDepartment of Communications, Polytechnic University, 300006 Timisoara, Romania.
Alis DemaDepartment of Pathology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-0767-2718
Ioan SporeaDepartment of Gastroenterology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · ROPolytechnic University of Timişoara · ROWest University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Objective: To design an artificial intelligence system for prostate cancer prediction using the data obtained by shear wave elastography of the prostate, by comparing it with the histopathological exam of the prostate biopsy specimens. (2) Material and methods: We have conducted a prospective study on 356 patients undergoing transrectal ultrasound-guided prostate biopsy, for suspicion of prostate cancer. All patients were examined using bi-dimensional shear wave ultrasonography, which was followed by standard systematic transrectal prostate biopsy. The mean elasticity of each of the twelve systematic biopsy target zones was recorded and compared with the pathological examination results in all patients. The final dataset has included data from 223 patients with confirmed prostate cancer. Three machine learning classification algorithms (logistic regression, a decision tree classifier and a dense neural network) were implemented and their performance in predicting the positive lesions from the elastographic data measurements was assessed. (3) Results: The area under the curve (AUC) results were as follows: for logistic regression-0.88, for decision tree classifier-0.78 and for the dense neural network-0.94. Further use of an upsampling strategy for the training set of the neural network slightly improved its performance. Using an ensemble learning model, which combined the three machine learning models, we have obtained a final accuracy of 98%. (4) Conclusions: Bi-dimensional shear wave elastography could be very useful in predicting prostate cancer lesions, especially when it benefits from the computational power of artificial intelligence and machine learning algorithms.

Indexed as

Elasticity Imaging TechniquesProstatic NeoplasmsArtificial IntelligenceBiopsyHumansMaleProspective Studiesartificial intelligence systemprostate cancershear wave elastography

Identifiers

PMID35735445
PMCPMC9221963
OpenAlexW4281893295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.