Evidence map›Paper›PMID 35735356›Full record

ArticleChemical research in toxicology2022

Effects of Common e-Liquid Flavorants and Added Nicotine on Toxicant Formation during Vaping Analyzed by

Paul J Kerber, Anna K Duell, Marley Powers, Robert M Strongin, David H Peyton

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paul J KerberDepartment of Chemistry, Portland State University, Portland, Oregon 97207-0751, United States.ORCID 0000-0001-8043-2636
Anna K DuellDepartment of Chemistry, Portland State University, Portland, Oregon 97207-0751, United States.ORCID 0000-0001-5855-5162
Marley PowersDepartment of Chemistry, Portland State University, Portland, Oregon 97207-0751, United States.
Robert M StronginDepartment of Chemistry, Portland State University, Portland, Oregon 97207-0751, United States.ORCID 0000-0003-3777-8492
David H PeytonDepartment of Chemistry, Portland State University, Portland, Oregon 97207-0751, United States.ORCID 0000-0001-5828-055X
Portland State University · US

Funding

Toxicant Production and Mitigation in the Electronic-Cigarette Reaction VesselR01ES025257 · NIEHS · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2015 to 2019
$3.6M
NIEHS NIH HHS R01 ES025257
6 · The paper itself

Abstract

A broad variety of e-liquids are used by e-cigarette consumers. Additives to the e-liquid carrier solvents, propylene glycol and glycerol, often include flavorants and nicotine at various concentrations. Flavorants in general have been reported to increase toxicant formation in e-cigarette aerosols, yet there is still much that remains unknown about the effects of flavorants, nicotine, and flavorants + nicotine on harmful and potentially harmful constituents (HPHCs) when aerosolizing e-liquids. Common flavorants benzaldehyde, vanillin, benzyl alcohol, and

Indexed as

Electronic Nicotine Delivery SystemsVapingAerosolsBenzaldehydesBenzyl AlcoholsFlavoring AgentsHazardous SubstancesMagnetic Resonance SpectroscopyNicotineAerosolsBenzaldehydesBenzyl AlcoholsFlavoring AgentsHazardous SubstancesNicotine

Identifiers

PMID35735356
PMCPMC10861143
OpenAlexW4283391214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.