Evidence map›Paper›PMID 35735230›Full record

ArticleDatabase : the journal of biological databases and curation2022

Centralizing neurofibromatosis experimental tool knowledge with the NF Research Tools Database.

Ashley Clayton, Mialy DeFelice, Brynn Zalmanek, Jay Hodgson, Caroline Morin, Stockard Simon, Julie A Bletz, James A Eddy, Milen Nikolov, Jineta Banerjee and 8 more

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ashley ClaytonSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Mialy DeFeliceSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Brynn ZalmanekSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Jay HodgsonSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Caroline MorinGilbert Family Foundation, 1074 Woodward Ave., Detroit, MI 48226, USA.
Stockard SimonSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Julie A BletzSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
James A EddySage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Milen NikolovSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Jineta BanerjeeSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Kalyan VinnakotaGilbert Family Foundation, 1074 Woodward Ave., Detroit, MI 48226, USA.
Marco MarascaSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Kevin J BoskeSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Bruce HoffSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
Ljubomir BradicSage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.
YooRi KimGilbert Family Foundation, 1074 Woodward Ave., Detroit, MI 48226, USA.
James R GossGilbert Family Foundation, 1074 Woodward Ave., Detroit, MI 48226, USA.
Robert J AllawaySage Bionetworks, 2901 Third Ave., Suite 330, Seattle, WA 98121, USA.ORCID 0000-0003-3573-3565

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental tools and resources, such as animal models, cell lines, antibodies, genetic reagents and biobanks, are key ingredients in biomedical research. Investigators face multiple challenges when trying to understand the availability, applicability and accessibility of these tools. A major challenge is keeping up with current information about the numerous tools available for a particular research problem. A variety of disease-agnostic projects such as the Mouse Genome Informatics database and the Resource Identification Initiative curate a number of types of research tools. Here, we describe our efforts to build upon these resources to develop a disease-specific research tool resource for the neurofibromatosis (NF) research community. This resource, the NF Research Tools Database, is an open-access database that enables the exploration and discovery of information about NF type 1-relevant animal models, cell lines, antibodies, genetic reagents and biobanks. Users can search and explore tools, obtain detailed information about each tool as well as read and contribute their observations about the performance, reliability and characteristics of tools in the database. NF researchers will be able to use the NF Research Tools Database to promote, discover, share, reuse and characterize research tools, with the goal of advancing NF research. Database URL: https://tools.nf.synapse.org/.

Indexed as

Biomedical ResearchNeurofibromatosesAnimalsDatabases, FactualMiceReproducibility of Results

Identifiers

PMID35735230
PMCPMC9218993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.