Evidence map›Paper›PMID 35735104›Full record

ArticleThe Journal of manual & manipulative therapy2023

Low-back related leg pain: is the nerve guilty? How to differentiate the underlying pain mechanism.

Antoine Fourré, Félix Monnier, Laurence Ris, Frédéric Telliez, Jef Michielsen, Nathalie Roussel, Renaud Hage

Registry-linked trialOpen access · hybridAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of manual & manipulative therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07573124 (Efficacy of Combining Mulligan's Spinal Mobilization With Leg Movement Technique and Mechanical Lumbar Traction Among Patients With Lumbar Radiculopathy), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07573124 narecruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of Combining Mulligan's Spinal Mobilization With Leg Movement Technique and Mechanical Lumbar Traction Among Patients With Lumbar Radiculopathy: A Randomized Controlled Trial

TypeinterventionalSponsorKhyber Medical University PeshawarRan2026 to 2026Enrolled32ConditionsLumbar RadiculopathyArmsSpinal Mobilization with Leg Movement (SMWLM), Mechanical Lumbar Traction, Conventional Physical Therapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Antoine FourréDepartment of Neurosciences, Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.ORCID 0000-0002-8494-4919
Félix MonnierDepartment of Neurosciences, Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.ORCID 0000-0001-8557-852X
Laurence RisDepartment of Neurosciences, Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.ORCID 0000-0002-2140-8297
Frédéric TelliezInstitut d'Ingénierie de la Santé-UFR de Médecine, Centre Universitaire de Recherche en Santé-Laboratoire Péritox, Université de Picardie Jules Verne, Amiens, France.ORCID 0000-0001-6815-6050
Jef MichielsenFaculty of Medicine and Health Sciences, Rehabilitation Sciences and Physiotherapy (MOVANT), University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-4353-6601
Nathalie RousselFaculty of Medicine and Health Sciences, Rehabilitation Sciences and Physiotherapy (MOVANT), University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-7409-878X
Renaud HageTraitement Formation Thérapie Manuelle (TFTM), Physiotherapy Center, Brussels, Belgium.ORCID 0000-0002-6556-0899
University of Mons · BEUniversity of Antwerp · BEHaute École Louvain en Hainaut · BEUniversité de Picardie Jules Verne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low back pain (LBP) that radiates to the leg is not always related to a lesion or a disease of the nervous system (neuropathic pain): it might be nociceptive (referred) pain. Unfortunately, patients with low-back related leg pain are often given a variety of diagnoses (e.g. 'sciatica'; 'radicular pain'; pseudoradicular pain"). This terminology causes confusion and challenges clinical reasoning. It is essential for clinicians to understand and recognize predominant pain mechanisms. This paper describes pain mechanisms related to low back-related leg pain and helps differentiate these mechanisms in practice using clinical based scenarios. We illustrate this by using two clinical scenarios including patients with the same symptoms in terms of pain localization (i.e. low-back related leg pain) but with different underlying pain mechanisms (i.e. nociceptive versus neuropathic pain).

Indexed as

Low Back PainNeuralgiaSciaticaHumansLegPain MeasurementReferred Painclinical reasoningnerve tissueNeuropathic painpain management

Identifiers

PMID35735104
PMCPMC10013353
OpenAlexW4283321724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.