Evidence map›Paper›PMID 35735082›Full record

ArticleBiomedical journal2021

T1 and T2∗ relaxation time in the parcellated myocardium of healthy Taiwanese participants: A single center study.

Chih-Chien Tsai, Shu-Hang Ng, Yao-Liang Chen, Yu-Hsiang Juan, Chao-Hung Wang, Gigin Lin, Chih-Wei Chien, Yu-Ching Lin, Yu-Chun Lin, Yu-Chieh Huang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Chih-Chien TsaiHealthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Shu-Hang NgDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.
Yao-Liang ChenDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Department of Diagnostic Radiology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Yu-Hsiang JuanDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Taoyuan, Taoyuan, Taiwan.
Chao-Hung WangDepartment of Cardiology and Heart Failure Center, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Gigin LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Institute for Radiological Research, Chang Gung University, Taoyuan, Taiwan.
Chih-Wei ChienDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Yu-Ching LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Department of Diagnostic Radiology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Yu-Chun LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.
Yu-Chieh HuangDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Pei-Ching HuangDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Jiun-Jie WangHealthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan; Department of Diagnostic Radiology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Medical Imaging Research Center, Institute for Radiological Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. Electronic address: jwang@mail.cgu.edu.tw.
Keelung Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TWChang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuantitative maps from cardiac MRI provide objective information for myocardial tissue. The study aimed to report the T1 and T2∗ relaxation time and its relationship with clinical parameters in healthy Taiwanese participants.

methodsNinety-three participants were enrolled between 2014 and 2016 (Males/Females: 43/50; age: 49.7 ± 11.3/49.9 ± 10.3). T1 and T2∗ weighted images were obtained by MOLLI recovery and 3D fully flow compensated gradient echo sequences with a 3T MR scanner, respectively. The T1 map of the myocardium was parcellated into 16 partitions from the American Heart Association. The septal part of basal, mid-cavity, and apical view was selected for the T2∗ map. The difference of quantitative map by sex and age groups were evaluated by Student's TTEST and ANOVA, respectively. The relationship between T1, T2∗ map, and clinical parameters, such as ejection fraction, pulse rate, and blood pressures, were evaluated with partial correlation by controlling BMI and age.

resultsMale participants decreased T1 relaxation time in partitions which located in the mid-cavity and apical before 55 years old compared with females (Male/Female: 1143.1.4 ± 72.0-1191.1 ± 37.0/1180.1 ± 54.5-1326.1 ± 113.3 msec, p < 0.01). For female participants, T1 relaxation time was correlated negatively with systolic pressure (p < 0.01) and pulse rate (p < 0.01) before 45 years old. Besides, T1 and T2∗ relaxation time were positively and negatively correlated with ejection fraction and pulse rate after 45 years old in male participants, respectively. Decreased T2∗ relaxation time could be noticed in participants after 45 years old compared with youngers (26.0 ± 6.5/21.9 ± 8.0 msec; 25.2 ± 5.0/21.6 ± 7.2 msec, p < 0.05).

conclusionReference T1 and T2∗ relaxation time from cardiac MRI in healthy Taiwanese participants were provided with sex and age-dependent manners. The relationship between clinical parameters and T1 or T2∗ relaxation time was also established and could be further investigated for its potential application in healthy/sub-healthy participants.

Indexed as

Magnetic Resonance ImagingAdultFemaleHealthy VolunteersHeartHumansMaleMiddle AgedMyocardiumReproducibility of ResultsVentricular Function, LeftCardiac MRIParcellated myocardiumQuantitative mappingRelaxation timeTaiwanese participants

Identifiers

PMID35735082
PMCPMC9039095
OpenAlexW3082575188

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.