Evidence map›Paper›PMID 35734974›Full record

Trial reportJournal of cellular and molecular medicine2022

A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease.

Geru Tao, Guangjie Zhang, Wei Chen, Chao Yang, Yazhuo Xue, Guohua Song, Shucun Qin

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Geru TaoThe Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.ORCID 0000-0003-4330-5149
Guangjie ZhangTaishan Institute for Hydrogen Biomedical Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
Wei ChenThe Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.
Chao YangTaishan Institute for Hydrogen Biomedical Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
Yazhuo XueTaishan Institute for Hydrogen Biomedical Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
Guohua SongTaishan Institute for Hydrogen Biomedical Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
Shucun QinThe Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.
Affiliated Hospital of Taishan Medical University · CNTaishan Medical University · CNHandan Polytechnic College · CN

Funding

Academic promotion program of Shandong First Medical University 2019QL010National Natural Science Foundation of China 81770855Taishan Scholars Foundation of Shandong Province ts201511057
6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide with increasing incidence consistent with obesity, type 2 diabetes and cardiovascular diseases. No approved medication was currently available for NAFLD treatment. Molecular hydrogen (H

Indexed as

Diabetes Mellitus, Type 2Non-alcoholic Fatty Liver DiseaseAnimalsAnti-Inflammatory AgentsHumansHydrogenLiverMiceMice, Inbred C57BLOxygenPalmitic AcidAnti-Inflammatory AgentsHydrogenOxygenPalmitic Acidautophagyclinical trialMCD-induced NASHmolecular hydrogenNAFLD

Identifiers

PMID35734974
PMCPMC9279585
OpenAlexW4283312951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.