Evidence map›Paper›PMID 35734962›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

Examining the lineage autonomous role of β3-integrin in muscle regeneration.

Nathalie Gerassimov, Colt Crain, Colin Bilyeu, Andrew Jacob, Chen-Ming Fan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Examining the lineage autonomous role of β3-integrin in muscle regeneration.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nathalie GerassimovDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA.
Colt CrainDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA.
Colin BilyeuDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA.
Andrew JacobSeraxis Inc., Germantown, Maryland, USA.
Chen-Ming FanDepartment of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA.ORCID 0000-0003-3211-6617
Carnegie Institution for Science · USJohns Hopkins University · USSenseonics (United States) · US

Funding

Integrin signaling in skeletal muscle regenerationR01AR071976 · NIAMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI FAN, CHEN-MING · 2017 to 2021
$1.8M
Proliferation competence of skeletal muscle stem cellsR01AR072644 · NIAMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI FAN, CHEN-MING · 2018 to 2022
$1.8M
NIAMS NIH HHS R01 AR071976NIAMS NIH HHS R01 AR072644
6 · The paper itself

Abstract

Skeletal muscles can regenerate over the lifetime from resident muscle stem cells (MuSCs). Interactions between MuSCs and extracellular matrix (ECM) proteins are essential for muscle regeneration. The best-known receptors for ECM proteins are integrins, a family composed of twenty-some heterodimeric combinations of an α- and a β-subunit. β1-integrin (encoded by Itgb1) is required for quiescence, proliferation, migration, and fusion of Pax7

Indexed as

Muscle DevelopmentMyoblastsAnimalsCell DifferentiationMiceMuscle, SkeletalSignal Transductiondifferentiationmousemuscle stem cellsregenerationβ1-integrinβ3-integrin

Identifiers

PMID35734962
PMCPMC9236161
OpenAlexW4283329862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.