Evidence map›Paper›PMID 35734879›Full record

ArticleTuberculosis and respiratory diseases2022

Barthel's Index: A Better Predictor for COVID-19 Mortality Than Comorbidities.

João Cordeiro da Costa, Maria Conceição Manso, Susana Gregório, Márcia Leite, João Moreira Pinto

Abstract read
In one paragraph

Article in Tuberculosis and respiratory diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

João Cordeiro da CostaHospital-Escola da Universidade Fernando Pessoa, Gondomar, Portugal.
Maria Conceição MansoFP-I3ID (FP-ENAS), Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, Gondomar, Portugal.
Susana GregórioHospital-Escola da Universidade Fernando Pessoa, Gondomar, Portugal.
Márcia LeiteHospital-Escola da Universidade Fernando Pessoa, Gondomar, Portugal.
João Moreira PintoHospital-Escola da Universidade Fernando Pessoa, Gondomar, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe most consistently identified mortality determinants for the new coronavirus 2019 (COVID-19) infection are aging, male sex, cardiovascular/respiratory diseases, and cancer. They were determined from heterogeneous cohorts that included patients with different disease severity and previous conditions. The main goal of this study was to determine if activities of daily living (ADL) dependence measured by Barthel's index could be a predictor for COVID-19 mortality.

methodsA prospective cohort study was performed with a consecutive sample of 340 COVID-19 patients representing patients from all over the northern region of Portugal from October 2020 to March 2021. Mortality risk factors were determined after controlling for demographics, ADL dependence, admission time, comorbidities, clinical manifestations, and delay-time for diagnosis. Central tendency measures were used to analyze continuous variables and absolute numbers (proportions) for categorical variables. For univariable analysis, we used t test, chi-square test, or Fisher exact test as appropriate (α=0.05). Multivariable analysis was performed using logistic regression. IBM SPSS version 27 statistical software was used for data analysis.

resultsThe cohort included 340 patients (55.3% females) with a mean age of 80.6±11.0 years. The mortality rate was 19.7%. Univariate analysis revealed that aging, ADL dependence, pneumonia, and dementia were associated with mortality and that dyslipidemia and obesity were associated with survival. In multivariable analysis, dyslipidemia (odds ratio [OR], 0.35; 95% confidence interval [CI], 0.17-0.71) was independently associated with survival. Age ≥86 years (pooled OR, 2.239; 95% CI, 1.100-4.559), pneumonia (pooled OR, 3.00; 95% CI, 1.362-6.606), and ADL dependence (pooled OR, 6.296; 95% CI, 1.795-22.088) were significantly related to mortality (receiver operating characteristic area under the curve, 82.1%; p<0.001).

conclusionADL dependence, aging, and pneumonia are three main predictors for COVID-19 mortality in an elderly population.

Indexed as

COVID-19ElderlyFrailtyInfectionsMortality

Identifiers

PMID35734879
PMCPMC9537660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.