Evidence map›Paper›PMID 35734851›Full record

ArticleBioengineered2022

microRNA-301a-3p is a potential biomarker in venous ulcers vein and gets involved in endothelial cell dysfunction.

Ying Wang, Jingchen Du, Yu Liu, Shuhui Yang, Qingshan Wang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Transcriptomics in Venous Leg Ulcers (VLU): A Systematic Review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
  2. Article
  3. Article
  4. Molecular Determinants of Chronic Venous Disease: A Comprehensive Review.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ying WangDepartment of Vascular Surgery, The Second Affiliated Hospital of Qiqihar Medical College, Qiqihar, Heilongjiang, China.
Jingchen DuDepartment of Vascular Surgery, Heilongjiang Provincial Hospital, Harbin, Heilongjiang, China.
Yu LiuDepartment of Vascular Surgery, The First Hospital of Qiqihar, Qiqihar, Heilongjiang, China.
Shuhui YangDepartment of Vascular Surgery, Heilongjiang Provincial Hospital, Harbin, Heilongjiang, China.
Qingshan WangDepartment of Vascular Surgery, Heilongjiang Provincial Hospital, Harbin, Heilongjiang, China.
Heilongjiang Provincial Hospital · CNQiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous ulcer is a common contributor to chronic venous insufficiency (CVI) of lower limbs, which seriously affects the life quality of patients. In this study, we researched the expression characteristics of microRNA-301a-3p (miR-301a-3p) in patients with CVI and investigated the impact of miR-301a-3p on the dysfunction of human umbilical vein endothelial cells (HUVECs). The plasma level of miR-301a-3p in normal controls, patients with varicose great saphenous vein, and patients with the venous ulcer of lower limbs were measured. We adopted Interleukin-1β (IL-1β), H

Indexed as

MicroRNAsVaricose UlcerApoptosisBiomarkersGlucoseHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideNF-kappa BPhosphatidylinositol 3-KinasesPPAR gammaProto-Oncogene Proteins c-aktBiomarkersGlucoseHydrogen PeroxideMicroRNAsMIRN301A microRNA, humanNF-kappa BPhosphatidylinositol 3-KinasesPPAR gammaProto-Oncogene Proteins c-aktendothelial cellsIGF1miR-301a-3pMMPsVenous ulcers

Identifiers

PMID35734851
PMCPMC9342147
OpenAlexW4283314548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.