Evidence map›Paper›PMID 35734346›Full record

ArticleBioMed research international2022

The Role of Methyl-(Z)-11-tetradecenoate Acid from the Bacterial Membrane Lipid Composition in

Alexandru O Doma, Romeo T Cristina, Florin Muselin, Eugenia Dumitrescu, János Dégi, Kálman Imre, Marius Boldea, Daliborca C Vlad, Roxana Popescu, Adinela Cimporescu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alexandru O DomaBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0001-5252-6969
Romeo T CristinaBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0002-5420-1516
Florin MuselinBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0003-2907-4233
Eugenia DumitrescuBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.
János DégiBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0002-5859-5057
Kálman ImreBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0002-6057-882X
Marius BoldeaBanat's University of Agricultural Sciences and Veterinary Medicine Timisoara, Calea Aradului 119, 300645 Timisoara, Romania.ORCID https://orcid.org/0000-0003-4943-0522
Daliborca C VladUniversity of Medicine and Pharmacy Timisoara, Piata Eftimie Murgu, 2, 300041 Timisoara, Romania.ORCID https://orcid.org/0000-0002-9243-1865
Roxana PopescuUniversity of Medicine and Pharmacy Timisoara, Piata Eftimie Murgu, 2, 300041 Timisoara, Romania.ORCID https://orcid.org/0000-0002-9387-1141
Adinela CimporescuUniversity of Medicine and Pharmacy Timisoara, Piata Eftimie Murgu, 2, 300041 Timisoara, Romania.
Dana C BratuUniversity of Medicine and Pharmacy Timisoara, Piata Eftimie Murgu, 2, 300041 Timisoara, Romania.ORCID https://orcid.org/0000-0002-2401-690X
Univesity of Life Science "King Mihai I" from Timisoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The bacterial membrane plays a critical role in the survival of bacteria and the effectiveness of antimicrobial peptides in protecting the host. The lipid constituents of the bacterial membrane are not evenly distributed, and they could be affected by clustering anionic lipids with cationic peptides with multiple positive charges. That could be harmful to bacteria because it prevents lipids from interacting with other molecular components of the cell membrane, disrupts existing natural domains, or creates phase boundary defects between the clustered lipids and the bulk of the membrane. This preliminary quantitative study is aimed at assembling a correlation between antibiotic resistance and bacterial lipid composition in Methods: Fifteen multiresistant Results: Interpreting the descriptive statistical method, the correlation matrix, and regression curves and after ANOVA analysis, we ascertained that the studied Conclusions: In one case, the methyl-(Z)-11-tetradecenoate acid was observed to have a relationship with the susceptibility evaluation by using the disc diffusimetric method, which has revealed the lowest rate of antimicrobial resistance, so it has importance in further resistance evaluation studies.

Indexed as

Escherichia coli InfectionsMembrane LipidsAnimalsAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialDrug Resistance, MicrobialEscherichia coliMicrobial Sensitivity TestsSwineAnti-Bacterial AgentsMembrane Lipids

Identifiers

PMID35734346
PMCPMC9209004
OpenAlexW4282838034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.