Evidence map›Paper›PMID 35734322›Full record

Observational studyThe Pan African medical journal2022

The epidemiological profile of meningitis among adults in a South African district hospital.

Kian Terwin, Mari Ferreira, Christiaan Minnie, Kalliopy Marangellis, Ruben Darby, Jesse Berlyn, Anél Kleingeld, Shezree Tiel, Matthew Olukayode Abiodun Benedict, Cornel van Rooyen and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Assessing teamwork perceptions and challenges in a South African district hospital.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
    Article
  4. Article
  5. Article
  6. Characteristics and Distribution of Fungal Meningitis: A Systematic Review.Infectious diseases & clinical microbiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kian TerwinUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Mari FerreiraUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Christiaan MinnieUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Kalliopy MarangellisUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Ruben DarbyUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Jesse BerlynUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Anél KleingeldUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Shezree TielUndergraduate Medical Programme, School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Matthew Olukayode Abiodun BenedictDepartment of Family, Medicine Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Cornel van RooyenDepartment of Biostatistics, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Anthonio Oladele AdefuyeDivision of Health Sciences Education, Office of the Dean, Faculty of Health Sciences, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
Joseph Bukulu SempaDepartment of Biostatistics, University of the Free State, PO Box 339, Bloemfontein, 9300, South Africa.
University of the Free State · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: understanding the epidemiological profile of a disease in a particular region allows for proper planning of public health resources for prevention, early diagnosis and treatment. In this present study, we describe the epidemiological profile of viral, fungal, tuberculous and bacterial meningitis among adults at National District Hospital (NDH), Free State province, over three years period (January 2017 to December 2019). Methods: a retrospective, observational study of all adult meningitis cases, managed at the National District Hospital (NDH) Bloemfontein, Free State Province, South Africa between January 2017 and December 2019. Results: of the 236 case files reviewed, majority (93.2%; n=220) of the patients managed for meningitis were black, as well as males (55.5%; n = 131). Higher incidence was found between the ages 20 to 49 (81.7%). Of those who died, the majority (n = 14; 63.6%) were males, in the age group 40-49 (n = 7; 31.8%), had TB meningitis (n = 12; 54.5%), were HIV positive (n = 20; 90.9%), and had cell count <100 cells/mm Conclusion: our study suggests that combining information on patient demography, co-morbidities, clinical presentation, and examination findings can substantially contribute to raising clinical suspicion, leading to swift identification, diagnosis, and treatment of patients.

Indexed as

HIV InfectionsMeningitis, BacterialTuberculosis, MeningealAdultFemaleHospitals, DistrictHumansMaleMiddle AgedRetrospective StudiesSouth AfricaYoung AdultadultFree StateMeningitisnational district hospital

Identifiers

PMID35734322
PMCPMC9188002
OpenAlexW4285740654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.