Evidence map›Paper›PMID 35734243›Full record

ArticleOpen access rheumatology : research and reviews2022

Biologic Initiation Rate in Systemic-Naïve Psoriatic Arthritis Patients Starting Treatment with Apremilast vs Methotrexate: 1-Year Retrospective Analysis of a US Claims Database.

M Elaine Husni, Eunice Chang, Michael S Broder, Caleb Paydar, Katalin Bognar, Pooja Desai, Yuri Klyachkin, Ibrahim Khilfeh

Open access · goldAbstract read
In one paragraph

Article in Open access rheumatology : research and reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

M Elaine HusniCleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-3181-4205
Eunice ChangPartnership for Health Analytic Research, LLC, Beverly Hills, CA, USA.ORCID 0000-0003-0177-6153
Michael S BroderPartnership for Health Analytic Research, LLC, Beverly Hills, CA, USA.ORCID 0000-0002-2049-5536
Caleb PaydarPartnership for Health Analytic Research, LLC, Beverly Hills, CA, USA.ORCID 0000-0003-1636-5947
Katalin BognarPartnership for Health Analytic Research, LLC, Beverly Hills, CA, USA.ORCID 0000-0001-8357-8569
Pooja DesaiAmgen Inc., Thousand Oaks, CA, USA.
Yuri KlyachkinAmgen Inc., Thousand Oaks, CA, USA.
Ibrahim KhilfehAmgen Inc., Thousand Oaks, CA, USA.ORCID 0000-0002-7677-2045
Partnership for Health Analytic Research · USAmgen (United States) · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the rate of biologic initiation after commencing treatment with apremilast (APR) vs methotrexate (MTX), in systemic-naïve patients with psoriatic arthritis (PsA). Patients and Methods: Systemic-naïve patients with PsA who started treatment with either APR or MTX between 01/01/2015 and 12/31/2018 were analyzed using claims data from the IBM Results: A total of 2116 patients with PsA newly treated with APR (n = 534) or MTX (n = 1582) were identified. Mean age was similar (50.5 vs 50.4; Conclusion: Systemic-naïve patients with PsA have a lower rate of, and longer time to, biologic initiation over one-year following APR initiation, compared to those initiating MTX.

Indexed as

administrative claims analysisbiologicsoral small moleculespsoriatic arthritissystemic treatment initiation

Identifiers

PMID35734243
PMCPMC9207121
OpenAlexW4282945431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.