Evidence map›Paper›PMID 35734228›Full record

ArticleCurrent research in toxicology2022

Current research in pathophysiology of opioid-induced respiratory depression, neonatal opioid withdrawal syndrome, and neonatal antidepressant exposure syndrome.

Brian A Baldo

Open access · goldAbstract read
In one paragraph

Article in Current research in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Respiratory Depression Associated with Opioids: A Narrative Review.Current treatment options in oncology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Opioid Overdose Detection in a Murine Model Using a Custom-Designed Photoplethysmography Device.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Brian A BaldoKolling Institute of Medical Research, Royal North Shore Hospital of Sydney and Department of Medicine, University of Sydney, Sydney, NSW, Australia.
Royal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory depression (RD) is the primary cause of death due to opioids. Opioids bind to mu (µ)-opioid receptors (MORs) encoded by the MOR gene

Indexed as

AAV, adeno-associated virusCDC, Centers for Disease control and preventionCTAP, MOR agonist (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2)DAMGO, synthetic specific MOR agonist [D-Ala2, N-MePhe4, Gly-ol]-enkephalinDRG, dorsal respiratory groupFDA, Food and Drug AdministrationGIRK, G protein-gated inwardly-rectifying potassium (K+)GPCR, G protein-coupled receptorKCNQ, voltage-gated potassium (Kv) channels in the KCNQ (Kv7) familyKF, Kölliker-Fuse nucleusKölliker-Fuse nucleus and opioid-induced respiratory depressionMOR, mu opioid receptorNADES, neonatal antidepressant exposure syndromeNAS, neonatal abstinence syndromeNeonatal opioid withdrawal syndromeNeural mediation of opioid-induced respiratory depressionNIH, National Institutes of HealthNK-1R, neurokinin-1 receptorNOWES, neonatal opioid withdrawal syndromeOAD, opioid analgesic drugOIRD, opioid-induced respiratory depressionPathophysiology of opioid-induced respiratory depressionPBL, lateral parabrachialPBN, parabrachial nucleuspreBötC, pre-Bötzinger complexPre-Bötzinger complex and opioid-induced respiratory depressionPRG, pontine respiratory groupRD, respiratory depressionTACR1, tachykinin receptor 1VRG, ventral respiratory group

Identifiers

PMID35734228
PMCPMC9207297
OpenAlexW4281621176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.