Evidence map›Paper›PMID 35734091›Full record

ArticlebioRxiv : the preprint server for biology2022

A single-component luminescent biosensor for the SARS-CoV-2 spike protein.

Matthew Ravalin, Heegwang Roh, Rahul Suryawanshi, G Renuka Kumar, John Pak, Melanie Ott, Alice Y Ting

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Matthew RavalinDepartment of Genetics, Stanford University, Stanford, CA, USA.
Heegwang RohDepartment of Chemistry, Stanford University, Stanford, CA, USA.
Rahul SuryawanshiGladstone Institutes, San Francisco, CA, USA.
G Renuka KumarGladstone Institutes, San Francisco, CA, USA.
John PakChan Zuckerberg Biohub, San Francisco, CA, USA.
Melanie OttGladstone Institutes, San Francisco, CA, USA.
Alice Y TingDepartment of Biology, Department of Genetics, Department of Chemistry, Stanford University, Stanford, CA, USA.
Gladstone Institutes · USChan Zuckerberg Initiative (United States) · USStanford University · US

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
NHGRI NIH HHS T32 HG000044
6 · The paper itself

Abstract

Many existing protein detection strategies depend on highly functionalized antibody reagents. A simpler and easier to produce class of detection reagent is highly desirable. We designed a single-component, recombinant, luminescent biosensor that can be expressed in laboratory strains of

Identifiers

PMID35734091
PMCPMC9216720
OpenAlexW4282963457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.