ArticleCurrent research in parasitology & vector-borne diseases2022
LLIN evaluation in Uganda project (LLINEUP): The fabric integrity, chemical content and bioefficacy of long-lasting insecticidal nets treated with and without piperonyl butoxide across two years of operational use in Uganda.
Article in Current research in parasitology & vector-borne diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 43 citations in OpenAlex.
- Trial
- Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya): enrolment characteristics of cohort children and households.Malaria journal · 2024Trial
- Trial
- Evaluating the attrition, fabric integrity and insecticidal durability of two dual active ingredient nets (InterceptorMalaria journal · 2023Trial
- Differential impact of dual-active ingredient long-lasting insecticidal nets on primary malaria vectors: a secondary analysis of a 3-year, single-blind, cluster-randomised controlled trial in rural Tanzania.The Lancet. Planetary health · 2023Trial
- Modelling the impact of mosquito bed net utilization on malaria transmission and evolution of pyrethroid resistance.PloS one · 2026Article
- Durability of the insecticidal activity of next-generation insecticide treated nets distributed for malaria control in Mozambique: Findings from the New Nets Project (2020-2022).PLOS global public health · 2026Article
- Durability study of VeeralinParasites & vectors · 2025Article
- Does washing insecticide-treated nets 20 times for experimental hut evaluations provide a suitable proxy for their end-of-life performance under household conditions?Parasites & vectors · 2025Article
- Simulating dynamic insecticide selection pressures for resistance management in mosquitoes assuming polygenic resistance.PLoS computational biology · 2025Article
- Evaluating the impact of two next-generation long-lasting insecticidal nets on malaria incidence in Uganda: an interrupted time-series analysis using routine health facility data.BMJ global health · 2025Article
- The impact of insecticide decay on the rate of insecticide resistance evolution for monotherapies and mixtures.Malaria journal · 2025Article
- Article
- Targeted distribution of long-lasting insecticidal nets by community health workers to sustain household coverage: A pilot feasibility study in Western Uganda.PLOS global public health · 2025Article
- LLIN Evaluation in Uganda Project (LLINEUP2) - Effect of long-lasting insecticidal nets (LLINs) treated with pyrethroid plus pyriproxyfen vs LLINs treated with pyrethroid plus piperonyl butoxide in Uganda: A cluster-randomised trial.PLOS global public health · 2025Article
- The experimental hut efficacy of next-generation insecticide-treated nets against pyrethroid-resistant malaria vectors after 12, 24 and 36 months of household use in Benin.Malaria journal · 2024Article
- Efficacy of PermaNetMalaria journal · 2024Article
- Review on the impacts of indoor vector control on domiciliary pests: good intentions challenged by harsh realities.Proceedings. Biological sciences · 2024Review
- Video-trackedRoyal Society open science · 2024Article
- Article
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Authors and funding
23 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long-lasting insecticidal nets (LLINs) supplemented with the synergist piperonyl butoxide have been developed in response to growing pyrethroid resistance; however, their durability in the field remains poorly described. A pragmatic cluster-randomised trial was embedded into Uganda's 2017-2018 LLIN distribution to compare the durability of LLINs with and without PBO. A total of 104 clusters (health sub-districts) were included with each receiving one of four LLIN products, two with pyrethroid + PBO (Olyset Plus and PermaNet 3.0) and two pyrethroid-only (Olyset Net and PermaNet 2.0). Nets were sampled at baseline, 12 and 25 months post-distribution to assess physical condition, chemical content, and bioefficacy. Physical condition was quantified using proportionate Hole Index and chemical content measured using high-performance liquid chromatography. Bioefficacy was assessed with three-minute World Health Organisation (WHO) Cone and Wireball assays using pyrethroid-resistant
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.