Evidence map›Paper›PMID 35733973›Full record

ArticleFrontiers in microbiology2022

Bile Salt Hydrolase Degrades β-Lactam Antibiotics and Confers Antibiotic Resistance on

Hiroyuki Kusada, Masanori Arita, Masanori Tohno, Hideyuki Tamaki

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Foods (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Review
  9. Evidence for the Worldwide Distribution of a Bile Salt Hydrolase Gene inInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Recent advances in drug delivery and formulation · 2024
    Article
  18. Article
  19. Article
  20. Frontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hiroyuki KusadaBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
Masanori AritaBioinformation and DDBJ Center, National Institute of Genetics, Mishima, Japan.
Masanori TohnoResearch Center of Genetic Resources, Core Technology Research Headquarters, National Agriculture and Food Research Organization, Tsukuba, Japan.
Hideyuki TamakiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
National Institute of Advanced Industrial Science and Technology · JPNational Agriculture and Food Research Organization · JPNational Institute of Genetics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bile salt hydrolase (BSH) is a well-characterized probiotic enzyme associated with bile detoxification and colonization of lactic acid bacteria in the human gastrointestinal tract. Here, we isolated a putative BSH (LpBSH) from the probiotic bacterium

Indexed as

antibiotic resistancebile salt hydrolaseLactobacillus paragasseriNtn-hydrolase family proteinpenicillin acylase

Identifiers

PMID35733973
PMCPMC9207391
OpenAlexW4281672846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.