Evidence map›Paper›PMID 35733922›Full record

ArticleJournal of immunology research2022

The Ratio of CD226 and TIGIT Expression in Tfh and PD-1

Ji-Wen Fan, Yu Fan, Zheng-Li Wan, Lin Yan, Ya-Mei Li, Yang-Juan Bai, Lan-Lan Wang, Jie Chen, Yi Li

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Total Alkaloids ofJournal of inflammation research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ji-Wen Fan *Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Yu Fan *Department of Urology, National Clinical Research Center for Geriatrics and Organ Transplantation Center, West China Hospital of Sichuan University, No. 37 Guoxue Xiang, Chengdu 610041, China.
Zheng-Li WanDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Lin YanDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Ya-Mei LiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Yang-Juan BaiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Lan-Lan WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Jie ChenDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-5663-7444
Yi LiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0003-0418-3521
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplantation is the ideal treatment for end-stage renal disease (ESRD). Chronic antibody-mediated rejection (CAMR) is the main cause of graft failure. Tfh and B cells are key immune cells that play important roles in CAMR. In this study, the populations of different Tfh cell phenotypes and B cell subsets in CAMR were investigated in a total of 36 patients. Based on Banff-2019, 15 patients were diagnosed with CAMR (CAMR group), 11 recipients were diagnosed with recurrent or de novo IgA nephropathy (IgAN group), and 10 patients displayed stable renal function (stable group). The Tfh and B cell subsets were analyzed by flow cytometry. The percentage and absolute number of PD-1

Indexed as

Glomerulonephritis, IGAGraft RejectionGraft vs Host DiseaseKidney TransplantationAntibodiesAntigens, Differentiation, T-LymphocyteBiomarkersHumansInducible T-Cell Co-Stimulator ProteinProgrammed Cell Death 1 ReceptorReceptors, ImmunologicT Follicular Helper CellsT Lineage-Specific Activation Antigen 1AntibodiesAntigens, Differentiation, T-LymphocyteBiomarkersICOS protein, humanInducible T-Cell Co-Stimulator ProteinProgrammed Cell Death 1 ReceptorReceptors, ImmunologicTIGIT protein, humanT Lineage-Specific Activation Antigen 1

Identifiers

PMID35733922
PMCPMC9206998
OpenAlexW4282565317

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.