Evidence map›Paper›PMID 35733918›Full record

ArticleJournal of immunology research2022

HIF-1

Yuanyuan Lyu, Yilin Zhang, Yuhan Wang, Yonghong Luo, Huafeng Ding, Peiling Li, Guantai Ni

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. The relevance of mJournal of cancer research and clinical oncology · 2026
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  5. mFrontiers in cell and developmental biology · 2026
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  8. Review
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  11. Article
  12. Review
  13. Targeting mCurrent oncology (Toronto, Ont.) · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. NImmunity, inflammation and disease · 2024
    Review
  19. Progression of mCell death discovery · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuanyuan LyuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Yilin ZhangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Yuhan WangDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086 Heilongjiang, China.
Yonghong LuoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Huafeng DingDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Peiling LiDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086 Heilongjiang, China.ORCID https://orcid.org/0000-0002-3041-1367
Guantai NiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.ORCID https://orcid.org/0000-0002-3956-2903
First Affiliated Hospital of Wannan Medical College · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenosine (m6A) RNA methylation has been determined to execute crucial functions in tumorigenesis and cancer development. WT1-associated protein (WTAP) has an important "writer" role in m6A modification, and it is also a nuclear protein that colocalizes with splicing factors and plays a critical role in cell function and cancer progression. However, little is known about the role of WTAP in ovarian cancer (OC) and its mechanisms. In this study, we found for the first time that hypoxia-inducible factor (HIF)-1

Indexed as

MicroRNAsOvarian NeoplasmsRNA Splicing FactorsAdenosineCell Cycle ProteinsFemaleHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitRNA-Binding ProteinsAdenosineCell Cycle ProteinsHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsMIRN200 microRNA, humanN-methyladenosineRNA-Binding ProteinsRNA Splicing FactorsWTAP protein, human

Identifiers

PMID35733918
PMCPMC9207020
OpenAlexW4282574102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.