Evidence map›Paper›PMID 35733861›Full record

ArticleFrontiers in medicine2022

Feasibility of Extracting Meaningful Patient Centered Outcomes From the Electronic Health Record Following Critical Illness in the Elderly.

Sumera R Ahmad, Alex D Tarabochia, Luann Budahn, Allison M Lemahieu, Brenda Anderson, Kirtivardhan Vashistha, Lioudmila Karnatovskaia, Ognjen Gajic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sumera R AhmadDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, United States.
Alex D TarabochiaDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Luann BudahnAnesthesia and Critical Care Research Unit, Mayo Clinic, Rochester, MN, United States.
Allison M LemahieuDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.
Brenda AndersonAnesthesia and Critical Care Research Unit, Mayo Clinic, Rochester, MN, United States.
Kirtivardhan VashisthaDepartment of Infectious Disease, Multi-disciplinary Epidemiology and Translational Research in Intensive Care Research Group, Mayo Clinic, Rochester, MN, United States.
Lioudmila KarnatovskaiaDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, United States.
Ognjen GajicDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic in Florida · USMayo Clinic · USMayo Clinic in Arizona · US

Funding

Psychological support based on positive suggestions in acute respiratory failure patientsK23HL146741 · NHLBI · MAYO CLINIC ROCHESTER · PI KARNATOVSKAIA, LIOUDMILA · 2020 to 2024
$929k
NHLBI NIH HHS K23 HL146741
6 · The paper itself

Abstract

Background: Meaningful patient centered outcomes of critical illness such as functional status, cognition and mental health are studied using validated measurement tools that may often be impractical outside the research setting. The Electronic health record (EHR) contains a plethora of information pertaining to these domains. We sought to determine how feasible and reliable it is to assess meaningful patient centered outcomes from the EHR. Methods: Two independent investigators reviewed EHR of a random sample of ICU patients looking at documented assessments of trajectory of functional status, cognition, and mental health. Cohen's kappa was used to measure agreement between 2 reviewers. Post ICU health in these domains 12 month after admission was compared to pre- ICU health in the 12 months prior to assess qualitatively whether a patient's condition was "better," "unchanged" or "worse." Days alive and out of hospital/health care facility was a secondary outcome. Results: Thirty six of the 41 randomly selected patients (88%) survived critical illness. EHR contained sufficient information to determine the difference in health status before and after critical illness in most survivors (86%). Decline in functional status (36%), cognition (11%), and mental health (11%) following ICU admission was observed compared to premorbid baseline. Agreement between reviewers was excellent (kappa ranging from 0.966 to 1). Eighteen patients (44%) remained home after discharge from hospital and rehabilitation during the 12- month follow up. Conclusion: We demonstrated the feasibility and reliability of assessing the trajectory of changes in functional status, cognition, and selected mental health outcomes from EHR of critically ill patients. If validated in a larger, representative sample, these outcomes could be used alongside survival in quality improvement studies and pragmatic clinical trials.

Indexed as

critical illnessdays alive and out of hospital/health care facility (DAOH)electronic health records (EHR)patient important outcomestrajectory

Identifiers

PMID35733861
PMCPMC9207323
OpenAlexW4281681442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.