Evidence map›Paper›PMID 35733832›Full record

ArticleFrontiers in toxicology2022

Accurate Evaluation of Hepatocyte Metabolisms on a Noble Oxygen-Permeable Material With Low Sorption Characteristics.

Masaki Nishikawa, Hiroyasu Ito, Fumiya Tokito, Keita Hirono, Kousuke Inamura, Benedikt Scheidecker, Mathieu Danoy, Takumi Kawanishi, Hirohsi Arakawa, Yukio Kato and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Masaki NishikawaDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Hiroyasu ItoDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Fumiya TokitoDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Keita HironoDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Kousuke InamuraDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Benedikt ScheideckerDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Mathieu DanoyDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
Takumi KawanishiFaculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Hirohsi ArakawaFaculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Yukio KatoFaculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Katsuhiro EsashikaFilm & Sheet Materials Depatment, Functional Materials Laboratory, R&D Center, Mitsuichemicals, Inc., Tokyo, Japan.
Hiroshi MiyasakoChemicals Safety Department, Responsible Care and Quality Assurance Div., Mitsuichemicals, Inc., Tokyo, Japan.
Yasuyuki SakaiDepartment of Chemical System Engineering, University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPKanazawa University · JPMitsubishi Materials (Japan) · JPMitsui (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the pharmaceutical industry, primary cultured hepatocytes is a standard tool used to assess hepatic metabolisms and toxicity

Indexed as

4-polymethyl-1-pentene polymerchemical sorptiondrug developmenthepatocyteoxygen supplyPDMStoxicity test

Identifiers

PMID35733832
PMCPMC9208656
OpenAlexW4281648096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.