Evidence map›Paper›PMID 35733813›Full record

ArticleFrontiers in pediatrics2022

Cannabidiol Reduces Inflammatory Lung Damage After Meconium Aspiration in Newborn Piglets.

Luis Arruza, Lorena Barata, Eva Vierge, Maria José Rodríguez, Aaron Del Pozo, William Hind, José Martínez-Orgado

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Luis ArruzaDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Lorena BarataDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Eva ViergeDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Maria José RodríguezDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Aaron Del PozoDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
William HindGW Research Ltd., Cambridge, United Kingdom.
José Martínez-OrgadoDepartment of Neonatology, Hospital Clinico San Carlos-Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESGW Pharmaceuticals (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To assess the effects of cannabidiol (CBD) on lung damage in a piglet model of meconium aspiration syndrome (MAS). Materials and Methods: Meconium aspiration syndrome was modelled in newborn piglets Results: Post-insult administration of CBD reduced MAS-induced deterioration of gas exchange, improving respiratory acidosis (final pH 7.38 ± 0.02, 7.22 ± 0.03 and 7.33 ± 0.03 and final pCO Conclusion: Cannabidiol reduces histologic lung damage and inflammation in a piglet model of MAS. This translates into improved gas exchange and blood pressure stability.

Indexed as

cannabidiolinflammationmeconium aspiration syndrome (MAS)piglettranslational research

Identifiers

PMID35733813
PMCPMC9207394
OpenAlexW4281626514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.