ArticleRSC advances2022
Synthesis of pH-responsive covalent organic frameworks nanocarrier for plumbagin delivery.
Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Potential of Covalent Organic Framework in Pharmacy and Biomedicine: Influence of Structure on Properties and Applications.ChemMedChem · 2026Review
- The phytochemical plumbagin: mechanism behind its "pleiotropic" nature and potential as an anticancer treatment.Archives of toxicology · 2024Review
- Hydrazone-functionalized nanoscale covalent organic frameworks as a nanocarrier for pH-responsive drug delivery enhanced anticancer activity.RSC advances · 2024Article
- Polymeric nanoparticles (PNPs) for oral delivery of insulin.Journal of nanobiotechnology · 2024Review
- Photoresponse of CVD grown crystalline quantum dot-embedded covalent organic framework thin film.RSC advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Covalent organic frameworks have attracted increasing attention in the fields of nanotechnology and nanoscience. However, the biomedical applications of COFs still remain less explored. Here, a new type of nanoscale covalent organic framework (COF-366) composite was prepared by a facile solvothermal method. The obtained material was characterized by powder X-ray diffraction (XRD), Fourier transform-infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The results showed that the COF-366 nanocarriers possess uniform spherical morphology with a diameter of 150 nm, which make them favourable for drug delivery. After the plumbagin encapsulation, an effective pH responsive release, high adsorption capacity, and good biocompatibility were achieved. These characteristics make nanoscale COF-366 an ideal material for drug delivery and reveal its promising application in biomedical applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.